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Ferrous glycinate

HCID 9837124
노트반응
기본 정보개요이름 및 식별자물성안전 및 규제화학 및 산업관련 반응화합물 노트
부분 구조 검색유사 구조 찾기

기본 정보

CAS
20150-34-9
표준 SMILES
NCC(=O)[O-].NCC(=O)[O-].[Fe+2]
InChIKey
GIPOFCXYHMWROH-UHFFFAOYSA-L
분자식
C4H8FeN2O4
평균 분자량
203.96 g/mol
단동위원소 질량
203.983342

개요

Ferrous bisglycinate is a chelate that is used as a source of dietary iron. Forming a ring structure when reacting with glycine, ferrous bisglycinate acts as both a chelate and a nutritionally functional. It is found in foods for food enrichment or in supplements for the treatment of iron deficiency or iron deficiency anemia.

이름 및 식별자

우선 이름
Ferrous glycinate
IUPAC
bis(2-aminoacetate);iron(2+)
영어명
Ferrous Bisglycinate
분자식
C4H8FeN2O4
분자량
203.96

이름 및 동의어

Ferrous bisglycinate20150-34-9FERROUS GLYCINATEIron Bis-glycinateBisglycino-iron(II) chelateIron bis-glycinate chelateDTXSID30173978SFW1D987QVRefChem:140305DTXCID2096469Bis(glycinato-kappaN,kappaO)ironiron trisglycinate
이름 더 보기
FERROCHELFerric GlycineFerrous GglycinateFerrous Bis-glycineIron(II) bisglycinateFERROUS(II) GLYCINATEFerric Glycine CoMplexBisglycine iron(II) salt
2-aminoacetate;iron(2+)MFCD07780318FERROUSBISGLYCINATEC4H8FeN2O4Iron(II) glycinateferrous;2-aminoacetateBis(2-aminoacetoxy)ironIron(2+) bis(aminoacetate)

데이터베이스 식별자

CAS
20150-34-9
PubChem CID
9837124
DTXSID
DTXSID30173978
ChEMBL
CHEMBL4297753
UNII
SFW1D987QV
EC Number

물성

구조 계산 물성

극성 표면적
132 Ų
수소 결합 공여자 수
2
수소 결합 수용자 수
6
회전 가능 결합 수
0
무거운 원자 수
11
형식 전하
0
복잡도
37.4

물리화학적 성질

녹는점
162 °C · >162°C (dec.)
끓는 점
150 ℃ · 150℃ at 101kPa
밀도
1.898 at · 1.898 at 20℃
증기압
0 · 0-0Pa at 20-25℃
저장 조건
Keep in dark place,Inert atmosphere,Room temperature
용해도
산성 용액(약간 용해됨)
물리적 상태
고체
색상
옅은 갈색에서 갈색까지
수용성
35.71 mg/mL · Water: 35.71 mg/mL (176.83 mM)
안정성
흡습성
화장품 원료 기능
피부 컨디셔닝항산화제
InChI
InChI=1S/2C2H4NO2.Fe/c2*3-1-2(4)5;/h2*3H,1H2,(H,4,5);/q2*-1;+4/p-2
InChIKey
MECJLZIFMOMXPW-UHFFFAOYSA-L
SMILES
O=C1CN[Fe+2]2(NCC(=O)[O-]2)[O-]1
LogP
-3.47 at · -3.47 at 20℃ and pH7
표면장력
72.87 mN/m · 72.87mN/m at 1g/L and 20℃

안전 및 규제

안전 정보는 참고용이며, 공급업체의 물질안전보건자료(SDS), 관련 법규 및 전문가 평가를 대체하지 않습니다.

GHS 분류

GHS Classification · 5건

This chemical does not meet GHS hazard criteria for 2.5% (4 of 162) of reports.

Warning

H302 (32.7%): Harmful if swallowed [Warning Acute toxicity, oral]

P261, P264, P264+P265, P270, P271, P273, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P317, P321, P330, P332+P317, P337+P317, P362+P364, P391, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 162 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

유해성 정보

Regulatory Information · 3건

Regulation (EC) No 178/2002 (amended)

REACH registered substance: Iron, bis(glycinato-.kappa.N,.kappa.O)- (EC: 606-444-7)

Ferrous bisglycinate: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.

Hazard Classes and CategoriesAcute Tox. 4 (32.7%)

안전 데이터

독성
LD50 orally in rats: 560 mg iron/kg (Jeppsen)

화학 및 산업

용도 및 제조

Use ClassificationFood Additives -> NUTRIENT_SUPPLEMENT -> JECFA Functional Classes
응용 분야 · 2건

개요Ferrous Bisglycinate, also known as ferrous glycinate, is an iron (II) chelate with an iron to glycine ratio of 1:2. It has an octahedral structure with two water molecules and two chelated glycinate ions coordinated to the central ferrous iron. Ferrous glycinate (processed with citric acid) also contains citric acid. It is manufactured by reaction of reduced iron with glycine in the presence of citric acid. The resulting product is spray dried without prior removal of the citric acid. The substance is highly hygroscopic and may contain water in variable amounts.

용도Ferrous Bisglycinate is an iron-amio acid chelate. In this the iron is protected from the action of absorption inhibitors by being bound to the amino acid and glycine. Ferrous bisglycinate is the major amino acid chelate produced commercially, although ferrous trisglycinate and ferric glycinate are also available. A patented ferrous bisglycinate compound, manufactured by Albion Laboratories, Utah, USA, has been used in most published studies. The chelate is reported to be formed by two glycine molecules combining with ferrous iron in a double heterocyclic ring structure. Evidence would suggest that iron is protected from inhibitors by the structure, since iron absorption is one to 3.5 times higher than from ferrous sulfate when added to bread rolls and milk products containing inhibitors such as phytate and calcium. Ferrous bisglycinate is more bioavailable than ferrous trisglycinate.

공급사108 곳

Shandong chuangyingchemical Co., Ltd.18853181302 · [email protected]
山东天微医药科技有限公司+86-18653895227 · [email protected]
上海康朗生物科技有限公司021-61998208 18217752821 · [email protected]

관련 반응

2건
반응 기록 만들기
HRID 387489 반응식
HRID 387489생성물로uspto-grants-2013_02
HRID 504074 반응식
HRID 504074반응물로uspto-grants-2010_08

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