트리플루오로초산 무수물

Trifluoroacetic anhydride

HCID 9845CAS 407-25-0
부분 구조 검색유사 구조 찾기

기본 정보

표준 SMILES
O=C(OC(=O)C(F)(F)F)C(F)(F)F
InChIKey
QAEDZJGFFMLHHQ-UHFFFAOYSA-N
분자식
C4F6O3
평균 분자량
210.03 g/mol
단동위원소 질량
209.97516318

이름 및 식별자

우선 이름
Trifluoroacetic anhydride
IUPAC
(2,2,2-trifluoroacetyl) 2,2,2-trifluoroacetate
현지명
트리플루오로초산 무수물
영어명
Trifluoroacetic anhydride
분자식
C4F6O3
분자량
210.03

이름 및 동의어

TRIFLUOROACETIC ANHYDRIDE407-25-0Trifluoroacetic acid anhydrideBis(trifluoroacetic) anhydridePerfluoroacetic anhydrideTrifluoroacetyl anhydrideHexafluoroacetic anhydrideAnhydrid kyseliny trifluoroctove5ENA87IZHTNSC-96965DTXSID90861920RefChem:899576
이름 더 보기
트라이플루오로아세트산무수물트리플루오로초산무수물트라이플루오로아세트산무수물trifluoroaceticTRIFLUORACETIC ANHYDRIDETIFLUOROACETIC ANHYDRIDETrifluoroacetic anhyTrifluoroacetic anhydride 10g [407-25-0]uoroacetic anhydridetrimethylamine (TMA)
DTXCID90810771206-982-9TFAA2,2,2-trifluoroacetic anhydrideAcetic acid, trifluoro-, anhydridetrifluoro acetic anhydride(2,2,2-trifluoroacetyl) 2,2,2-trifluoroacetate2,2,2-trifluoroacetyl 2,2,2-trifluoroacetate

데이터베이스 식별자

CAS
407-25-0
PubChem CID
9845
DTXSID
DTXSID90861920
UNII
5ENA87IZHT
EC Number
206-982-9
Nikkaji
J5.723A

물성

구조 계산 물성

XLogP
2.1
극성 표면적
43.4 Ų
수소 결합 공여자 수
0
수소 결합 수용자 수
9
회전 가능 결합 수
2
무거운 원자 수
13

실험 및 물리화학적 성질

Chemical ClassesOther Classes -> Acid Anhydrides, Other
PFAS · 2건

PFAS -> PFAS identified in REACH Regulation EC No. 1272/2008

PFAS -> Suspected persistent, mobile, toxic (PMT) PFAS or PFAS-like compounds

SpringerMaterials PropertiesSchoenflies notation
Density1.49 @25 °C
Boiling Point39.5 °C @760 [mm Hg]
Vapor Pressure41.2 [mmHg]

물리화학적 성질

녹는점
-65 °C · -65 °C (lit.)
끓는 점
39.5 · 39.5-40 °C (lit.)
밀도
1.511 g/mL · 1.511 g/mL at 20 °C (lit.)
증기압
6.28 psi · 6.28 psi ( 20 °C)
굴절률
20 · n20/D 1.3(lit.)
인화점
-26 °C · -26 °C

화학적 성질

Clear, colorless liquid

안전 및 규제

GHS 분류

GHS Classification · 4건

Danger

H314 (100%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]

P203, P260, P261, P264, P264+P265, P271, P273, P280, P301+P330+P331, P302+P361+P354, P304+P340, P305+P354+P338, P316, P317, P318, P321, P363, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 114 reports by companies from 21 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

유해성 정보

Regulatory Information · 4건

Chemical: Acetic acid, trifluoro-, anhydride

Acetic acid, 2,2,2-trifluoro-, 1,1'-anhydride is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Acetic acid, 2,2,2-trifluoro-, 1,1'-anhydride are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Status: Active Update: 29-04-2019 https://echa.europa.eu/registration-dossier/-/registered-dossier/10848

Trifluoroacetic anhydride: HSNO Approval: HSR004742 Approved with controls

Hazards SummaryCorrosive to skin; [eChemPortal: ERMA] Reacts with water; A corrosive substance that can cause injury to the skin, eyes, and respiratory tract; Inhalation may cause chemical pneumonitis; [MSDSonline]
Hazard Classes and CategoriesSkin Corr. 1A (100%)

안전 및 보호

Protective Action Criteria (PAC) · 3건

0.60 [mg/m3]

6.6 [mg/m3]

40 [mg/m3]

독성 정보

Adverse EffectsDermatotoxin - Skin burns.

안전 데이터

wgk
2
tsca
TSCA listed
rtecs
AJ9800000
ridadr
UN 3265 8/PG 1
독성
skn-rbt 500 mg/24H SEV 28ZPAK -,91,72
HS 번호
29159080

화학 및 산업

용도 및 제조

U.S. Production2023: <50,000 lb
Industry UsesIntermediate
General Manufacturing Information · 2건

Miscellaneous Manufacturing

Acetic acid, 2,2,2-trifluoro-, 1,1'-anhydride: ACTIVE

응용 분야 · 4건

용도분석 시약, 용매, 촉매, 탈수 응축기, 카르복시기 및 아미노 트리 플루오로 아세틸 화를위한 보호제로 사용됩니다.

용도이는 분석 시약, 용매, 촉매, 탈수 축합 제, 카르복실기 및 아미노기의 트리 플루오로 아세틸 화를위한 보호제; 및 유기 불소 정밀 화학제, 약제 및 농약 제조용 원료를 제공한다.

용도분석 시약, 용매, 촉매, 탈수 응축기, 카르복시기 및 아미노 트리 플루오로 아세틸 화를위한 보호제로 사용됩니다.

용도Trifluoroacetic anhydride is used for the introduction of trifluoroacetyl group in organic synthesis. It is involved in the preparation of N- and O-trifluoroacetyl derivatives of a wide range of biologically active compounds for gas chromatography analysis. It plays an important role as desiccant for trifluoroacetic acid. It is also used in the oxidation of aldehydes to acids, esters, amides as well as in the protection of alcohols and amines. In addition, it is used as analytical reagents, solvents and dehydration condensing agent. It serves as an intermediate of fluorine fine chemicals, pharmaceuticals and agrochemicals.

제조 방법

Trifluoroacetic anhydride is prepared by reaction of trifluoroacetyl chloride with an alkali metal or alkaline-earth metal salt of trifluoroacetic acid at approximately 50° C.

상·하류 제품 정보

하류 제품

1-[4-(Trifluoromethyl)pyrimid-2-yl]piperazine2-Cyano-4-pyridine carboxylic acid2-히드록시-4-(트리플루오로메틸)피리미딘2-하이드록시메틸-5-브로모피리딘2-(4-Methylpiperazin-1-yl)-6-(trifluoromethyl)pyrimidine-4-carbonitrile2-Chloro-4-(trifluoromethyl)pyrimidine[BIS(TRIFLUOROACETOXY)IODO]펜타플루오로벤젠6-아미노벤조티아졸2-Hydroxy-6-(trifluoromethyl)nicotinic acid2-(4-Methylpiperazin-1-yl)-6-(trifluoromethyl)pyrimidine-4-carboxamide(2-(4-Methylpiperazin-1-yl)-6-(trifluoromethyl)pyrimidin-4-yl)methanamine2,6-Dichloro-4-isocyanatopyridine

공급사50 곳

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