기본 정보
- CAS
309712-55-8- 표준 SMILES
Cc1ccc(CN2CCNCC2)cc1NC(=O)CNc1ccc(F)c(F)c1.Cl.Cl.Cl- InChIKey
WSBRAHWNJBXXJM-UHFFFAOYSA-N- 분자식
- C20H27Cl3F2N4O
- 평균 분자량
- 483.8 g/mol
- 단동위원소 질량
- 482.121851
이름 및 식별자
- 우선 이름
- GW791343 trihydrochloride
- IUPAC
- 2-(3,4-difluoroanilino)-N-[2-methyl-5-(piperazin-1-ylmethyl)phenyl]acetamide;trihydrochloride
- 영어명
- GW791343 HCl
- 분자식
- C20H27Cl3F2N4O
- 분자량
- 483.8103864
이름 및 동의어
309712-55-8GW791343 trihydrochlorideGW791343 HCl1019779-04-4GW 791343 TrihydrochlorideGW791343 (trihydrochloride)2-(3,4-difluoroanilino)-N-[2-methyl-5-(piperazin-1-ylmethyl)phenyl]acetamide;trihydrochloride2-[(3,4-Difluorophenyl)amino]-N-[2-methyl-5-(1-piperazinylmethyl)phenyl]-acetamide trihydrochlorideGW 791343 DIHYDROCHLORIDEGW791343 (HCL)MFCD12828767GW-791343 hydrochloride
이름 더 보기
GW791343 HCl USP/EP/BPGW-791343 TRIHYDROCHLORIDE2-(3,4-difluorophenylamino)-N-(2-methyl-5-(piperazin-1-ylmethyl)phenyl)acetamide trihydrochloride2-((3,4-difluorophenyl)amino)-N-(2-methyl-5-(piperazin-1-ylmethyl)phenyl)acetamide hydrogen chloride
C20H27Cl3F2N4OGW791343 3HCl2-(3,4-difluoroanilino)-N-[2-methyl-5-(piperazin-1-ylmethyl)phenyl]acetamideGW791343 hydrochlorideGW 791343 TriHClGW791343 trihydrochloride?orb1685654SCHEMBL7242843
데이터베이스 식별자
- CAS
309712-55-8- PubChem CID
- 9848159
물성
구조 계산 물성
- 극성 표면적
- 56.4 Ų
- 수소 결합 공여자 수
- 6
- 수소 결합 수용자 수
- 6
- 회전 가능 결합 수
- 6
- 무거운 원자 수
- 30
- 형식 전하
- 0
- 복잡도
- 475
물리화학적 성질
- 저장 조건
- -20 °C · Store at -20°C
- 용해도
- 100 mM · Soluble to 100 mM in water and to 100 mM in DMSO
- 물리적 상태
- 가루
화학 및 산업
응용 분야
용도GW 791343 Trihydrochloride is a P2X7 receptor antagonist that acts as an allosteric inhibitor, exhibiting negative allosteric effects at the human P2X7 receptor and positive allosteric effects at the rat P2X7 receptor. P2X7 receptor is responsible for the presence of inflammatory cells, regulated by extracellular ATP.
공급사37 곳
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MedBio脉铂医药021-69568360 18916172912 · [email protected]
MedChemexpress LLC021-58955995 · [email protected]
Wuhan NCE Biomedical Co.,Ltd.4000-027-021 |24 +86-13986109188 | +86-15623472865 | +81-08033611988
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