아크릴로일 모폴린
아크릴로일모폴린 · 아크릴로일몰포린 · 1-(4-모폴리닐)-2-프로펜-1-온 · 아크릴로일 모폴린 · 1-(모폴린-4-일)프로펜온 · 4-(1-옥소-2-프로펜일)모폴린 · 4-아크릴로일모폴린 · N-아크릴로일모폴린
식별자 및 물리적 특성
| CAS No. | 5117-12-4 |
|---|---|
| 분자식 | C7H11NO2 |
| 평균 분자량 | 141.17 g/mol |
| 단동위원소 질량 | 141.07897859 g/mol |
| SMILES | C=CC(=O)N1CCOCC1 |
| InChIKey | XLPJNCYCZORXHG-UHFFFAOYSA-N |
| PubChem CID | 98723 |
| ChEMBL | CHEMBL3187188 |
| EC No. | 418-140-1 |
| DTXSID | DTXSID0044947 |
| 현지명 | 아크릴로일 모폴린 |
화학 및 물리적 성질
| XLogP | -0.1 |
|---|---|
| 극성 표면적 | 29.5 |
| 수소 결합 공여자 수 | 0 |
| 수소 결합 수용자 수 | 2 |
| 회전 가능 결합 수 | 1 |
| 무거운 원자 수 | 10 |
| 형식 전하 | 0 |
| 복잡도 | 139 |
| 녹는점 | −35 °C(lit.) |
| 끓는 점 | 158°C 50mm |
| 밀도 | 1.122 g/mL at 25 °C(lit.) |
| 증기압 | 1.03-1.64Pa at 25-29.9℃ |
| 굴절률 | n20/D 1.512(lit.) |
| 인화점 | >230 °F |
| 저장 조건 | 2-8°C |
| 용해도 | 물에 용해됨 |
| 물리적 상태 | 액체 |
| pKa(산도 계수) | -1.08±0.20(Predicted) |
| 색상 | 무색~황색 |
| 용해도 | 1000g/L at 20℃ |
| BRN | 119302 |
| 화장품 원료 기능 | 가소제 |
| InChI | 1S/C7H11NO2/c1-2-7(9)8-3-5-10-6-4-8/h2H,1,3-6H2 |
| InChIKey | XLPJNCYCZORXHG-UHFFFAOYSA-N |
| SMILES | C=CC(=O)N1CCOCC1 |
| LogP(분배 계수) | -0.46 at 20.5-21℃ |
| NIST | N-acryloylmorpholine(5117-12-4) |
| EPA | Morpholine, 4-(1-oxo-2-propenyl)- (5117-12-4) |
화학적 성질
4-Acryloylmorpholine has a melting point of 35 °C and is clear liquid at room temperature. At 25 °C, it has a density of 1.122 g/mL. It needs to be stored at 2-8°C.
안전 및 규제
| GHS 분류 | DangerH302: Harmful if swallowed [Warning Acute toxicity, oral]P260, P261, P264, P264+P265, P270, P272, P280, P301+P317, P302+P352, P305+P354+P338, P317, P319, P321, P330, P333+P317, P362+P364, and P501 (click each P-code to see the statement)H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]P260, P261, P264, P264+P265, P270, P271, P272, P280, P301+P317, P302+P352, P304+P340, P305+P354+P338, P316, P317, P319, P321, P330, P333+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement) |
|---|---|
| 규제 정보 | Chemical: Morpholine, 4-(1-oxo-2-propenyl)-PMN - indicates a commenced PMN (Pre-Manufacture Notices) substance.Status: No longer Valid Update: 10-11-2008 https://echa.europa.eu/registration-dossier/-/registered-dossier/9420Acryloyl morpholine: Does not have an individual approval but may be used under an appropriate group standard |
| 기타 안전 정보 | Evaluation - Morpholine, 4-(1-oxo-2-propenyl)- (acryloyl morpholine) |
| Hazard Classes and Categories | Acute Tox. 4 (100%)Acute toxicity - category 4Acute toxicity (Oral) - Category 4Acute Tox. 4 * |
| 수질 위해 등급(WGK) | 2 |
| TSCA 등재 상태 | TSCA listed |
| 관세 코드 | 29349990 |
| 위험 문구(R) | 22-41-43-48/22 |
| 위험 표시 | Xn |
| 안전 문구(S) | 23-26-36/37/39 |
| 기존화학 물질 | 2000-3-1524 |
| 위험 등급 | Acute Tox. 4 OralEye Dam. 1Skin Sens. 1STOT RE 2 Oral |
| 저장 분류 | 10 - Combustible liquids |
용도
용도
접착제, 자외선 경화 수지, 산업용 코팅, UV 인쇄 잉크, 오일 회수 폴리머, 의약 및 필수 화학 물질에 사용됩니다.
개요
4-Acryloylmorpholine (4-AM) is a water-soluble monomer, an acrylamide derivative containing a heterocyclic tetrahydrooxazine substituent. Homo- and copolymers of 4-АМ have several valuable properties. They are soluble both in water and in many organic solvents such as alcohols, chloroform, tetrahydrofuran, and dioxane, are non-toxic, and are used for solid-phase synthesis of peptides in chromatography, as materials for composite semipermeable membranes, in catalysis, and for biomedical purposes. Various functional groups are introduced into poly-4-AM to expand its application fields. Random copolymers of 4-АМ with carboxylic acids (acrylic, 4-pentenoic, undecenoic, 2-acrylamido-2-methyl-1-propanesulfonic), behaving as anionic polyelectrolytes, and copolymers with N-hydroxysuccinimide ester of acrylic acid, acting as polymeric carriers, have been synthesized[2-3].
용도
4-Acryloylmorpholine is used in adhesives, UV curable resins, industrial coatings, UV printing ink, oil recovery polymer, medicinal and commodity chemicals.