Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
퍼플루오로카프릴일브로마이드
퍼플루오로카프릴일브로마이드 · PFOB · perflubron · PERFLUOROOCTYL BROMIDE · Imagent · 1-BROMOPERFLUOROOCTANE · n-Perfluorooctyl bromide · HEPTADECAFLUORO-N-OCTYL BROMIDE
식별자 및 물리적 특성
| CAS No. | 423-55-2 |
|---|---|
| 분자식 | C8BrF17 |
| 평균 분자량 | 498.96 g/mol |
| 단동위원소 질량 | 497.89119 g/mol |
| SMILES | FC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)Br |
| InChIKey | WTWWXOGTJWMJHI-UHFFFAOYSA-N |
| PubChem CID | 9873 |
| ChEMBL | CHEMBL1200866 |
| ChEBI | CHEBI:38803 |
| EC No. | 207-028-4 |
| DTXSID | DTXSID5046560 |
| 현지명 | 퍼플루오로카프릴일브로마이드 |
화학 및 물리적 성질
| XLogP | 6.9 |
|---|---|
| 극성 표면적 | 0 |
| 수소 결합 공여자 수 | 0 |
| 수소 결합 수용자 수 | 17 |
| 회전 가능 결합 수 | 6 |
| 무거운 원자 수 | 26 |
| 형식 전하 | 0 |
| 복잡도 | 527 |
| Kovats Retention Index | 581 |
| 녹는점 | 6 °C |
| 끓는 점 | 142 °C(lit.) |
| 밀도 | 1.93 g/mL at 25 °C(lit.) |
| 증기압 | 12.8-72hPa at 25-65℃ |
| 굴절률 | n20/D 1.305(lit.) |
| 인화점 | 141-143°C |
| 저장 조건 | Sealed in dry,Room Temperature |
| 용해도 | DMSO에 용해됨 |
| 물리적 상태 | 점성 용액 |
| 비중 | 1.930 |
| 색상 | 무색~황갈색 |
| 용해도 | 물에 섞이거나 혼합하기 어렵지 않습니다. |
| Merck | 14,7156 |
| BRN | 2016022 |
| 화장품 원료 기능 | 용제 |
| InChI | 1S/C8BrF17/c9-7(22,23)5(18,19)3(14,15)1(10,11)2(12,13)4(16,17)6(20,21)8(24,25)26 |
| InChIKey | WTWWXOGTJWMJHI-UHFFFAOYSA-N |
| SMILES | FC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)Br |
| LogP(분배 계수) | 6.1 at 25℃ |
| EPA | 1-Bromoheptadecafluorooctane (423-55-2) |
화학적 성질
clear colorless liquid
안전 및 규제
| GHS 분류 | WarningH315 (90.9%): Causes skin irritation [Warning Skin corrosion/irritation]H319 (90.9%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]H335 (89.1%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposureRespiratory tract irritation]P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 55 reports by companies from 9 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.H413: May cause long lasting harmful effects to aquatic life [Hazardous to the aquatic environment, long-term hazard] |
|---|---|
| 규제 정보 | Status: Active Update: 22-10-2018 https://echa.europa.eu/registration-dossier/-/registered-dossier/23055 |
| Hazard Classes and Categories | Skin Irrit. 2 (90.9%)Eye Irrit. 2 (90.9%)STOT SE 3 (89.1%)Hazardous to the aquatic environment (Long-term) - Category 4 |
| 수질 위해 등급(WGK) | 3 |
| RTECS 번호 | RG8700000 |
| 운송 번호(UN) | 2810 |
| 독성 | LD50 i.v. in female rats: 41 g/kg (Burgan) |
| 관세 코드 | 29037800 |
| 위험 문구(R) | 36/37/38 |
| 위험 표시 | Xi |
| 안전 문구(S) | 26-37/39 |
| 포장분류 | III |
| 위험 등급 | 6.1(b)Eye Irrit. 2Skin Irrit. 2STOT SE 3 |
| 위험 참고 사항 | Irritant |
| 저장 분류 | 10 - Combustible liquids |
용도
용도
1-BroMoheptadecafluorooctane can be used as oxygen carrier in emulsions used as blood substitutes.
일반 설명
1-Bromoheptadecafluorooctane (perfluorooctyl bromide) is a perfluorocarbon. Poly(ethylene glycol)ylated polyester nanocapsules of perfluorooctyl bromide were surface-decorated with a RGD (arginine-glycine-aspartic acid) peptide, were used for tumor imaging. Nanocapsules of perfluorooctyl bromide have been developed as dual contrast agent for ultrasonography and Magnetic Resonance Imaging (MRI).