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기본 정보
- CAS
642-15-9- 표준 SMILES
CCCCCC[C@H]1C(=O)O[C@H](C)[C@H](NC(=O)c2cccc(NC=O)c2O)C(=O)O[C@@H](C)[C@@H]1OC(=O)C(C)CC.CCCCCC[C@H]1C(=O)O[C@H](C)[C@H](NC(=O)c2cccc(NC=O)c2O)C(=O)O[C@@H](C)[C@@H]1OC(=O)CC(C)C- 분자식
- C28H40N2O9
- 평균 분자량
- 548.63 g/mol
이름 및 식별자
- 우선 이름
- ANTIMYCIN A1
- 현지명
- 항마이신A1
- 영어명
- ANTIMYCIN A1
- 분자식
- C28H40N2O9
- 분자량
- 548.63
이름 및 동의어
항마이신A1dihydrosamidinANTIMYCIN A11,5-Dioxonane butanoic acid deriv.-dioxo-1,5-dioxonan-3-yl)salicylamideisovalericacid,8-esterwith3-formamido-n-(7-hexyl-8-hydroxy-4,9-dimethyl-2,63-(3-formamidosalicylamido)-8-hexyl-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl isovalerate[3-[(3-formamido-2-hydroxybenzoyl)amino]-8-hexyl-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl] 3-methylbutanoate[3-[(3-formamido-2-hydroxy-phenyl)carbonylamino]-8-hexyl-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl] 3-methylbutanoate3-methylbutyric acid [3-[(3-formamido-2-hydroxy-benzoyl)amino]-8-hexyl-4,9-diketo-2,6-dimethyl-1,5-dioxonan-7-yl] ester3-Methylbutyric acid 3-[[3-(formylamino)-2-hydroxybenzoyl]amino]-8-hexyl-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl ester
데이터베이스 식별자
- CAS
642-15-9- PubChem CID
- 9876702
물성
물리화학적 성질
- 녹는점
- 149.5 ℃ · 149.5℃
- 끓는 점
- 620.81 °C · 620.81°C (rough estimate)
- 밀도
- 1.2468 · 1.2468 (rough estimate)
- 굴절률
- 1.58 · 1.5800 (estimate)
- 저장 조건
- 20 °C · −20°C
- 용해도
- DMF: Soluble; DMSO: Soluble; Ethanol: Soluble; Methanol: Soluble
- 물리적 상태
- 고체
화학적 성질
Crystals. Soluble in alcohol, ether, acetone, and chloroform; slightly soluble in benzene, carbon tetrachloride, and petroleum ether; insoluble in water.
안전 및 규제
안전 정보는 참고용이며, 공급업체의 물질안전보건자료(SDS), 관련 법규 및 전문가 평가를 대체하지 않습니다.
안전 데이터
- rtecs
- NY1503500
- ridadr
- 3172
- risk_code
- 23/24/25
- hazard_code
- T
- safety_code
- 36/37/39-45
- 포장분류
- II
- 위험 등급
- 6.1(a)
화학 및 산업
응용 분야
개요Antimycin A1 is an active component of the antimycin A antibiotic complex. It inhibits electron transport and is active against the plant pathogenic fungus G. cingulate. Antimycin A1 (3.3-160 μM) induces the synthesis of carotenoids in M. marinum. It also inhibits ATP-citrate lyase (Ki = 29.5 μM).
용도Antimycin A1 is the most hydrophobic of the four analogues of the antimycin A complex. Like all antimycins, antimycin A1 exhibits potent antifungal, anthelmintic, insecticidal, antiviral and antitumor activity across a range of bioassays. Although broadly active as respiration inhibitors, more recent investigation has highlighted the importance of individual members of the complex as bioprobes. Antimycin A1 inhibits angiogenesis via a decrease in VEGF production caused by inhibition of HIF-1a activation.
공급사25 곳
Career Henan Chemica Co+86-0371-86658258 +86-13203830695 · [email protected]
武汉英诺医药科技有限公司+86-027-59232304 15387063101 · [email protected]
上海优宁维生物科技股份有限公司15921930842 15921930842 · [email protected]
上海赛可锐生物科技有限公司021-58000709 13120558703 · [email protected]
安耐吉化学&3A（安徽泽升科技有限公司）021-58432009 400-005-6266 · [email protected]
孟成科技（上海）有限公司400-820-6829 · [email protected]
湖北魏氏化学试剂股份有限公司027-59102966 18717199209 · [email protected]
MedBio脉铂医药021-69568360 18916172912 · [email protected]
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