Hexafluoropropylene oxide (HCID 9883)

개요

Hexafluoropropylene oxide is a colorless odorless gas. It is shipped as a liquefied gas under its vapor pressure. Contact with the liquid can cause frostbite. Its vapors are heavier than air. It can cause asphyxiation by the displacement of air. Exposure of the container to prolonged heat or fire may cause it to rupture violently and rocket.

이름 및 식별자

우선 이름: Hexafluoropropylene oxide
IUPAC: 2,2,3-trifluoro-3-(trifluoromethyl)oxirane
현지명: 헥사플루오로프로펜 산화물
영어명: Hexafluoropropylene oxide
분자식: C3F6O
분자량: 166.02

이름 및 동의어

Hexafluoropropylene oxide428-59-1Hexafluoropropene oxide2,2,3-Trifluoro-3-(trifluoromethyl)oxiraneHfpoTRIFLUORO(TRIFLUOROMETHYL)OXIRANEPerfluoropropylene oxideHexafluoro-1,2-epoxypropaneHexafluoropropene epoxideHexafluoropropylene epoxideHexafluoroepoxypropanePropylene oxide hexafluoride

이름 더 보기

헥사플루오로프로펜산화물헥사플루오로프로펜산화물(HEXAFLUOROPROPENEOXIDE)1,1,2,3,3,3-Hexafluoro-1,2-epoxypropaneC3F6ONA 1956(S) TRIMETHYLOXIRANE

Oxirane, trifluoro(trifluoromethyl)-JPY12AP87NPropane, 1,2-epoxy-1,1,2,3,3,3-hexafluoro-RefChem:146014ACETONE, HEXAFLUOROHFPO hexafluoropropylene oxide207-050-4Poly(perfluoropropyleneoxide)

데이터베이스 식별자

CAS: 428-59-1
PubChem CID: 9883
DTXSID: DTXSID6029177
UNII: JPY12AP87N
EC Number: 207-050-4
Nikkaji: J27.198E

물성

구조 계산 물성

XLogP: 2.1
극성 표면적: 12.5 Å²
수소 결합 공여자 수: 0
수소 결합 수용자 수: 7
회전 가능 결합 수: 0
무거운 원자 수: 10
형식 전하: 0
복잡도: 161

실험 및 물리화학적 성질

PFAS · 6건

PFAS -> OECD Category

PFAS -> Suspected persistent, mobile, toxic (PMT) PFAS or PFAS-like compounds

PFAS

PFAS -> Intentionally added food contact chemicals

PFAS -> PFAS identified in REACH Regulation EC No. 1272/2008

PFAS -> Other/unspecified

PolymersPlastics & Rubber -> Other Monomers

Boiling Point-18 °F at 760 mmHg (NTP, 1992)

Decomposition · 1건

AT TEMP BETWEEN 500-800 °C, CARBONYL FLUORIDE (COF2) IS DOMINANT PYROLYSIS PRODUCT. THIS GAS IS VERY SUSCEPTIBLE TO HYDROLYSIS, READILY YIELDING HYDROFLUORIC ACID & CARBON DIOXIDE. ABOVE 800 °C, THE PYROLYSIS PRODUCTS CONSIST OF INORGANIC FLUORIDE, A LITTLE TETRAFLUOROMETHANE & CARBON DIOXIDE. /POLYFLUORINES/

Melting Point-200 °F (NTP, 1992)

Physical Description · 3건

Hexafluoropropylene oxide is a colorless odorless gas. It is shipped as a liquefied gas under its vapor pressure. Contact with the liquid can cause frostbite. Its vapors are heavier than air. It can cause asphyxiation by the displacement of air. Exposure of the container to prolonged heat or fire may cause it to rupture violently and rocket.

Gas Vapor; CBI; Liquid

Colorless odorless gas; Shipped liquefied under its vapor pressure; [CAMEO]

물리화학적 성질

녹는점: -129 °C · -129°C
끓는 점: 42 °C · −42 °C(lit.)
밀도: 1.67 · 1.67±0.1 g/cm3(Predicted)
증기압: 680.85 kPa · 680.85kPa at 25℃
수용성: 16.3 μg/L · 16.3μg/L at 22.7℃
Henry's Law Constant: 9.3 · 9.3×10-6 mol/(m3Pa) at 25℃, Clever et al. (2005)
InChI: InChI=1S/C3F6O/c4-1(2(5,6)7)3(8,9)10-1
InChIKey: PGFXOWRDDHCDTE-UHFFFAOYSA-N
SMILES: O1C(F)(C(F)(F)F)C1(F)F
LogP: 1.72 at · 1.72 at 25℃
NIST: Oxirane, trifluoro(trifluoromethyl)-(428-59-1)
EPA: 2 · Oxirane, 2,2,3-trifluoro-3-(trifluoromethyl)- (428-59-1)

안전 및 규제

GHS 분류

GHS Classification · 6건

This chemical does not meet GHS hazard criteria for 24.2% (16 of 66) of reports.

Danger

H280 (74.2%): Contains gas under pressure; may explode if heated [Warning Gases under pressure]

P260, P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P316, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, P410+P403, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 66 reports by companies from 8 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Danger

유해성 정보

Regulatory Information · 4건

Oxirane, 2,2,3-trifluoro-3-(trifluoromethyl)- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Oxirane, 2,2,3-trifluoro-3-(trifluoromethyl)- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

S - indicates a substance that is identified in a final Significant New Use Rule.

Status: Active Update: 21-01-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/5721

The New Jersey Worker and Community Right to Know Act requires public and private employers to provide information about hazardous substances at their workplaces. (N.J.S.A. 34:5A-1 et. seq.)

DOT LabelNon-Flammable Gas

Fire HazardsExcerpt from ERG Guide 126 [Gases - Compressed or Liquefied (Including Refrigerant Gases)]:

Health HazardsExcerpt from ERG Guide 126 [Gases - Compressed or Liquefied (Including Refrigerant Gases)]:

Hazards Summary · 1건

May polymerize; Containers may explode from prolonged heat; Evaporating liquid can cause frostbite; In confined space spill, may displace air and act as simple asphyxiant; [CAMEO] May explode if heated under confinement; An irritant; In confined space spill, may displace air and act as simple asphyxiant; [MSDSonline]

Reactive GroupEpoxides

안전 및 보호

Fire FightingExcerpt from ERG Guide 126 [Gases - Compressed or Liquefied (Including Refrigerant Gases)]:

First Aid · 1건

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Nonfire Spill ResponseExcerpt from ERG Guide 126 [Gases - Compressed or Liquefied (Including Refrigerant Gases)]:

Preventive Measures · 1건

VENTILATION CONTROL: ...WHERE...RESINS ARE LIKELY TO UNDERGO PYROLYSIS & DECOMP DURING PROCESSING, PROVISION SHOULD BE MADE FOR ADEQUATE LOCAL EXHAUST & GENERAL VENTILATION TO KEEP CONCN OF DECOMP PRODUCTS AS LOW AS POSSIBLE. /POLYFLUORINES/

Isolation and EvacuationExcerpt from ERG Guide 126 [Gases - Compressed or Liquefied (Including Refrigerant Gases)]:

Personal Protective Equipment (PPE)Excerpt from ERG Guide 126 [Gases - Compressed or Liquefied (Including Refrigerant Gases)]:

독성 정보

Adverse EffectsOther Poison - Simple Asphyxiant

Human Toxicity Excerpts · 1건

A UNIQUE EFFECT FROM PYROLYSIS PRODUCTS OF PTFE /POLYTETRAFLUOROETHYLENE/ RESINS...BEEN OBSERVED IN MAN... THIS IS AN INFLUENZA-LIKE SYNDROME RESEMBLING METAL FUME FEVER & HAS BEEN TERMED "POLYMER FUME FEVER". IT IS SELF-LIMITING, LASTS...24-48 HR & REQUIRES ONLY SYMPTOMATIC TREATMENT. /POLYFLUORINES/

Non-Human Toxicity Excerpts · 1건

IN ACUTE STUDIES WITH MICE & RATS IT CAUSED CHANGES IN LIVER & KIDNEY. IN SPLEEN IT CAUSED VASCULAR PERMEABILITY & DEGENERATIVE DYSTROPHIC CHANGES & INFLAMMATION. EXTENT & NATURE OF TOXICITY DEPENDS UPON TYPE OF METABOLITES THAT ARE PRODUCED.

Probable Routes of Human Exposure · 1건

A UNIQUE EFFECT FROM PYROLYSIS PRODUCTS OF PTFE /POLYTETRAFLUOROETHYLENE/ RESINS...BEEN OBSERVED IN MAN... THIS IS AN INFLUENZA-LIKE SYNDROME RESEMBLING METAL FUME FEVER & HAS BEEN TERMED "POLYMER FUME FEVER". IT IS SELF-LIMITING, LASTS...24-48 HR & REQUIRES ONLY SYMPTOMATIC TREATMENT. /POLYFLUORINES/

안전 데이터

wgk: 3
tsca: TSCA listed
ridadr: UN 1956 2.2
risk_code: 36/37/38-44
hazard_code: Xi
safety_code: 7-26-37/39-38
위험 등급: 2.2
기존화학 물질: KE-28148
위험 참고 사항: Irritant
유해 물질 데이터: 428-59-1(Hazardous Substances Data)

화학 및 산업

용도 및 제조

Uses · 2건

Used as monomer for heat-resistant hexafluoropropylene oxide polymers; [HSDB]

MONOMER FOR HEXAFLUOROPROPYLENE OXIDE POLYMERS THAT ARE HEAT RESISTANT TO 410 °C

U.S. Production2023: 2,500,000 - <4,000,000 lb

Industry UsesIntermediate

Methods of ManufacturingOXIDATION OF HEXAFLUOROPROPYLENE WITH ALKALINE HYDROGEN PEROXIDE...ABOUT -30 °C.

Use ClassificationPFAS (per- and polyfluoroalkyl substances) -> OECD Category

General Manufacturing Information · 4건

All Other Basic Organic Chemical Manufacturing

Oxirane, 2,2,3-trifluoro-3-(trifluoromethyl)-: ACTIVE

"FREON E" /IS/ TRADEMARK FOR SERIES OF HYDROGEN END-CAPPED TETRAFLUOROETHYLENE EPOXIDE POLYMERS HAVING A DP /DEGREE OF POLYMERIZATION/ UP TO 10. BOILING RANGE 39-490 °C. HIGH DIELECTRIC CONSTANT. USED AS COOLANTS IN ELECTRONIC DEVICES. /FREON E/

"KRYTOX" /IS/ TRADEMARK FOR A SERIES OF HEXAFLUOROPROPYLENE EPOXIDE POLYMERS OF MEDIUM MOLECULAR WT, USED AS LUBRICATING OILS & GREASES. FOR USE IN HIGH TEMP OR CORROSIVE CONDITIONS; GOOD CHEM INERTNESS, EVEN WITH BOILING SULFURIC ACID; LOW SOLUBILITY IN MOST SOLVENTS; GOOD LUBRICITY UNDER LOAD... /KRYTOX/

응용 분야 · 2건

용도Hexafluoropropylene oxide is an important intermediate of organic fluorine material.HFPO is mainly used in the manufacture of high-quality fluorinated compounds.It is the main component of perfluor-vinyl ether(PPVE,PSVE,PFVE,PMVE) and the monomer of fluorinated surfactants and fluorinated ether oil.

일반 설명Hexafluoropropylene oxide is a colorless odorless gas. Hexafluoropropylene oxide is shipped as a liquefied gas under its vapor pressure. Contact with the liquid can cause frostbite. Its vapors are heavier than air. Hexafluoropropylene oxide can cause asphyxiation by the displacement of air. Exposure of the container to prolonged heat or fire may cause Hexafluoropropylene oxide to rupture violently and rocket.