기본 정보
- CAS
114876-72-1- 표준 SMILES
C/C=C\C1=C(C(=O)O)N2C(=O)[C@@H](NC(=O)[C@H](N)c3ccc(O)cc3)[C@H]2SC1.O- InChIKey
ALYUMNAHLSSTOU-HERYOFLYSA-N- 분자식
- C18H21N3O6S
- 평균 분자량
- 407.4 g/mol
- 단동위원소 질량
- 407.11510657
개요
Cefprozil, (Z)- is an Z-isomer of a semi-synthetic cephalosporin and a beta-lactam antibiotic with bactericidal activity. Cefprozil's effect is dependent on its binding to penicillin-binding proteins (PBPs) located in the bacterial cytoplasmic membrane. Binding results in the inhibition of the transpeptidase enzymes, thereby preventing cross-linking of the pentaglycine bridge with the fourth residue of the pentapeptide and interrupting consequent synthesis of peptidoglycan chains. As a result, cefprozil inhibits bacterial septum and cell wall synthesis formation.
이름 및 식별자
- 우선 이름
- Cefprozil, (Z)-
- IUPAC
- (6R,7R)-7-[[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino]-8-oxo-3-[(Z)-prop-1-enyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;hydrate
- 현지명
- 세프프로질(Z)-이성질체(200mg)
- 영어명
- Cefprozil (Z)-Isomer (200 mg)
- 분자식
- C18H21N3O6S
- 분자량
- 407.44
이름 및 동의어
Cefprozil, (Z)-114876-72-1UNII-358K60B00HCefprozil (Z)-Isomer358K60B00HCEFPROZIL, Z-ISOMER5-THIA-1-AZABICYCLO(4.2.0)OCT-2-ENE-2-CARBOXYLIC ACID, 7-(((2R)-2-AMINO-2-(4-HYDROXYPHENYL)ACETYL)AMINO)-8-OXO-3-(1Z)-1-PROPEN-1-YL-, HYDRATE (1:1), (6R,7R)-5-THIA-1-AZABICYCLO(4.2.0)OCT-2-ENE-2-CARBOXYLIC ACID, 7-((AMINO(4-HYDROXYPHENYL)ACETYL)AMINO)-8-OXO-3-(1-PROPENYL)-, MONOHYDRATE, (6R-(3(Z),6.ALPHA.,7.BETA.(R*)))-RefChem:1242485-THIA-1-AZABICYCLO(4.2.0)OCT-2-ENE-2-CARBOXYLIC ACID, 7-((AMINO(4-HYDROXYPHENYL)ACETYL)AMINO)-8-OXO-3-(1-PROPENYL)-, MONOHYDRATE, (6R-(3(Z),6ALPHA,7BETA(R*)))-(6R,7R)-7-[[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino]-8-oxo-3-[(Z)-prop-1-enyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;hydrate(Z)-cefprozil hydrate
이름 더 보기
세프프로질(Z)-이성질체(200mg)CefprozilImpurity16-Isomer)Cefprozil Impurity 16（Cefprozil (Z)-Isomer）
SCHEMBL37022Cefprozil (Z)-Isomer monohydrateQ27256443(6R,7R)-7-((R)-2-Amino-2-(p-hydroxyphenyl)acetamido)-8-oxo-3-(1Z)-propenyl-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid monohydrate
데이터베이스 식별자
- CAS
114876-72-1- PubChem CID
- 9887643
- UNII
- 358K60B00H
물성
구조 계산 물성
- 극성 표면적
- 159 Ų
- 수소 결합 공여자 수
- 5
- 수소 결합 수용자 수
- 8
- 회전 가능 결합 수
- 5
- 무거운 원자 수
- 28
- 형식 전하
- 0
- 복잡도
- 699
화학 및 산업
공급사10 곳
济南百隆化学有限公司[email protected] · [email protected]
广州佳途科技股份有限公司81960175-877 18933936954 · [email protected]
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上海尺水药物研究有限公司[email protected] 13564957716 · [email protected]
台州川旭医药科技有限公司[email protected] 15165038510 · [email protected]
Standardpharm Co. Ltd.86-714-3992388 · [email protected]
湖北扬信医药科技有限公司15374522761 · [email protected]
深圳市祥根生物医药有限公司0755-28967200 13631290199 · [email protected]
深圳纽柯尔化学技术有限公司13612807752 · [email protected]
湖北清北云研医药科技有限责任公司18162595016; 18162595016 · [email protected]
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