AM-36
기본 정보
- CAS
199467-52-2- 표준 SMILES
CC(C)(C)c1cc(CN2CCN(CC(O)c3ccc(Cl)cc3)CC2)cc(C(C)(C)C)c1O- InChIKey
ZGSFWANJADAZQC-UHFFFAOYSA-N- 분자식
- C27H39ClN2O2
- 평균 분자량
- 459.1 g/mol
- 단동위원소 질량
- 458.2700062
이름 및 식별자
- 우선 이름
- AM-36
- IUPAC
- 2,6-ditert-butyl-4-[[4-[2-(4-chlorophenyl)-2-hydroxyethyl]piperazin-1-yl]methyl]phenol
- 영어명
- 1-Piperazineethanol, 4-[[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]methyl]-α-(4-chlorophenyl)-, hydrochloride (1:2)
- 분자식
- C27H39ClN2O2
- 분자량
- 459.06
이름 및 동의어
AM-36199467-52-2AM36 compoundCNSB002AM 3608OBY024NYCNSB-0021-Piperazineethanol, 4-((3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl)methyl)-alpha-(4-chlorophenyl)-RefChem:199533UNII-08OBY024NYCNSB 0021-(2-(4-chlorophenyl)-2-hydroxy)ethyl-4-(3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl)methylpiperazine
이름 더 보기
AM-36 DIHYDROCHLORIDE1-Piperazineethanol, 4-[[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]methyl]-α-(4-chlorophenyl)-2,6-DI-TERT-BUTYL-4-(4-[2-(4-CHLORO-PHENYL)-2-HYDROXY-ETHYL]-PIPERAZIN-1-YLMETHYL)-PHENOL DIHYDROCHLORIDE1-Piperazineethanol, 4-[[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]methyl]-α-(4-chlorophenyl)-, hydrochloride (1:2)
2,6-ditert-butyl-4-[[4-[2-(4-chlorophenyl)-2-hydroxyethyl]piperazin-1-yl]methyl]phenolorb1698501SCHEMBL12311270DTXSID601365641ZHA46752AKOS040750381NCGC00386490-014-((4-(2-(4-chlorophenyl)-2-hydroxyethyl)-1-piperazinyl)methyl)-2,6-bis(2-methyl-2-propanyl)phenol
데이터베이스 식별자
- CAS
199467-52-2- PubChem CID
- 9890390
- DTXSID
DTXSID601365641- UNII
- 08OBY024NY
- Nikkaji
- J1.152.023E
물성
구조 계산 물성
- XLogP
- 6
- 극성 표면적
- 46.9 Ų
- 수소 결합 공여자 수
- 2
- 수소 결합 수용자 수
- 4
- 회전 가능 결합 수
- 7
- 무거운 원자 수
- 32
- 형식 전하
- 0
- 복잡도
- 547
물리화학적 성질
- 끓는 점
- 542.5 · 542.5±45.0 °C(Predicted)
- 밀도
- 1.127 · 1.127±0.06 g/cm3(Predicted)
- 산도 계수 (pKa)
- 12.05 · 12.05±0.40(Predicted)
화학 및 산업
약리 정보
MeSH Pharmacological Classification
Naturally occurring or synthetic substances that inhibit or retard oxidation reactions. They counteract the damaging effects of oxidation in animal tissues.
Drugs intended to prevent damage to the brain or spinal cord from ischemia, stroke, convulsions, or trauma. Some must be administered before the event, but others may be effective for some time after. They act by a variety of mechanisms, but often directly or indirectly minimize the damage produced by endogenous excitatory amino acids.
A class of drugs that act by inhibition of sodium influx through cell membranes. Blockade of sodium channels slows the rate and amplitude of initial rapid depolarization, reduces cell excitability, and reduces conduction velocity.
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