N-(피페리딘-4-일)-4'-(트리플루오로메틸)-[1,1'-비페닐]-2-카르복스아미드

N-(Piperidin-4-yl)-4'-(trifluoromethyl)-biphenyl-2-carboxamide

HCID 9928271CAS 182439-41-4

부분 구조 검색 유사 구조 찾기

기본 정보

표준 SMILES: O=C(NC1CCNCC1)c1ccccc1-c1ccc(C(F)(F)F)cc1
InChIKey: AQANXBKFOZBCIY-UHFFFAOYSA-N
분자식: C19H19F3N2O
평균 분자량: 348.4 g/mol

이름 및 식별자

우선 이름: N-(Piperidin-4-yl)-4'-(trifluoromethyl)-biphenyl-2-carboxamide
IUPAC: N-piperidin-4-yl-2-[4-(trifluoromethyl)phenyl]benzamide
현지명: N-(피페리딘-4-일)-4'-(트리플루오로메틸)-[1,1'-비페닐]-2-카르복스아미드
영어명: N-(piperidin-4-yl)-4'-(trifluoromethyl)-[1,1'-biphenyl]-2-carboxamide
분자식: C19H19F3N2O
분자량: 348.36

이름 및 동의어

182439-41-4N-(Piperidin-4-yl)-4'-(trifluoromethyl)-biphenyl-2-carboxamideLomitapide metabolite M1BP7YFS63H2UNII-BP7YFS63H2N-4-Piperidinyl-4'-(trifluoromethyl)(1,1'-biphenyl)-2-carboxamide(1,1'-Biphenyl)-2-carboxamide, N-4-piperidinyl-4'-(trifluoromethyl)-[1,1'-Biphenyl]-2-carboxamide, N-4-piperidinyl-4'-(trifluoromethyl)-RefChem:202045N-(Piperidin-4-yl)-4'-(trifluoromethyl)biphenyl-2-carboxamideN-(PIPERIDIN-4-YL)-4'-(TRIFLUOROMETHYL)-[1,1'-BIPHENYL]-2-CARBOXAMIDEN-piperidin-4-yl-2-[4-(trifluoromethyl)phenyl]benzamide

이름 더 보기

N-(피페리딘-4-일)-4'-(트리플루오로메틸)-[1,1'-비페닐]-2-카르복스아미드N-4-Piperidinyl-4'-(trifluoromethyl)-[1,1'-biphenyl]-2-carboxamideN-(piperidin-4-yl)-4'-(trifluoromethyl)-[1,1'-biphenyl]-2-carboxamideethyl)-[1,1'-biphenyl]-2-carboxamido)piperidin-1-yl)butyl)-9H-fluorene-9-carboxamide

MFCD27978680N-(piperidin-4-yl)-4-(trifluoromethyl)biphenyl-2-carboxamideLomitapide M1SCHEMBL593798orb3218332DB-4034494-(4'-Trifluoromethylbiphenyl-2-carbonylamino)piperidineN-(4-Piperidinyl)-4'-(trifluoromethyl)-2-biphenylcarboxamide

데이터베이스 식별자

CAS: 182439-41-4
PubChem CID: 9928271
UNII: BP7YFS63H2

물성

구조 계산 물성

XLogP: 3.8
극성 표면적: 41.1 Å²
수소 결합 공여자 수: 2
수소 결합 수용자 수: 5
회전 가능 결합 수: 3
무거운 원자 수: 25
형식 전하: 0
복잡도: 440

물리화학적 성질

끓는 점: 480.8 · 480.8±45.0 °C(Predicted)
밀도: 1.27 · 1.27±0.1 g/cm3(Predicted)
저장 조건: Store at Room Tem.
산도 계수 (pKa): 14.06 · 14.06±0.20(Predicted)

안전 및 규제

안전 데이터

HS 번호: 2933399990

화학 및 산업

응용 분야 · 1건

용도N-(Piperidin-4-yl)-4''-(trifluoromethyl)-biphenyl-2-carboxamide is a reagent used in the preparation of lomitapide mesylate crystal forms. Lomitapide mesylate is a microsomal triglyceride transfer protein inhibitor which can lower the level of low density lipoprotein cholesterol in plasma. Lomitapide (L469435) metabolite.