기본 정보
- CAS
317318-84-6- 표준 SMILES
Cc1cc(SCc2sc(-c3ccc(C(F)(F)F)c(F)c3)nc2C)ccc1OCC(=O)O- InChIKey
HWVNEWGKWRGSRK-UHFFFAOYSA-N- 분자식
- C21H17F4NO3S2
- 평균 분자량
- 471.5 g/mol
- 단동위원소 질량
- 471.05859828
개요
GW 0742 is a monocarboxylic acid.
이름 및 식별자
- 우선 이름
- GW-0742
- IUPAC
- 2-[4-[[2-[3-fluoro-4-(trifluoromethyl)phenyl]-4-methyl-1,3-thiazol-5-yl]methylsulfanyl]-2-methylphenoxy]acetic acid
- 영어명
- GW0742
- 분자식
- C21H17F4NO3S2
- 분자량
- 471.49
이름 및 동의어
GW0742GW 0742GW-0742{4-[({2-[3-Fluoro-4-(Trifluoromethyl)phenyl]-4-Methyl-1,3-Thiazol-5-Yl}methyl)sulfanyl]-2-Methylphenoxy}acetic AcidDTXSID90407604PZK9FJC4ZDTXCID7020760(4-(((2-(3-FLUORO-4-(TRIFLUOROMETHYL)PHENYL)-4-METHYL-1,3-THIAZOL-5-YL)METHYL)SULFANYL)-2-METHYLPHENOXY)ACETIC ACIDRefChem:922624317318-84-6GW0742XGW610742
이름 더 보기
CS-2560GW 0742XGWdelta 0742Sarms Gw0742GW0742 sarmsGW0742 / GW0742GW0742(GW610742)GW0742 USP/EP/BP
GW-0742XMFCD07369423CHEMBL38508GW 6107422-(4-(((2-(3-Fluoro-4-(trifluoromethyl)phenyl)-4-methylthiazol-5-yl)methyl)thio)-2-methylphenoxy)acetic acid2-[4-[[[2-[3-fluoro-4-(trifluoromethyl)phenyl]-4-methyl-5-thiazolyl]methyl]thio]-2-methylphenoxy]acetic acid[4-[[[2-[3-fluoro-4-(trifluoromethyl)phenyl]-4-methyl-5-thiazolyl]methyl]thio]-2-methyl phenoxy]-acetic acid2-[4-[[2-[3-fluoro-4-(trifluoromethyl)phenyl]-4-methyl-1,3-thiazol-5-yl]methylsulfanyl]-2-methylphenoxy]acetic acid
데이터베이스 식별자
물성
구조 계산 물성
- XLogP
- 6
- 극성 표면적
- 113 Ų
- 수소 결합 공여자 수
- 1
- 수소 결합 수용자 수
- 10
- 회전 가능 결합 수
- 7
- 무거운 원자 수
- 31
- 형식 전하
- 0
- 복잡도
- 612
실험 및 물리화학적 성질
Collision Cross Section199.5 Ų [M-H]- [CCS Type: DT; Buffer gas: N2; Ionization: ESI-; Dataset: TOXCAST; Source Identifier: DTXSID9040760]
물리화학적 성질
- 녹는점
- 134.5 · 134.5-135.5 °C
- 끓는 점
- 591.5 · 591.5±60.0 °C(Predicted)
- 밀도
- 1.46 · 1.46±0.1 g/cm3(Predicted)
- 저장 조건
- 2 · 2-8°C
- 용해도
- 5 mg/mL · DMSO: >5mg/mL
- 물리적 상태
- 고체
- 산도 계수 (pKa)
- 3.17 · 3.17±0.10(Predicted)
- 색상
- 하얀색
- InChI
- InChI=1S/C21H17F4NO3S2/c1-11-7-14(4-6-17(11)29-9-19(27)28)30-10-18-12(2)26-20(31-18)13-3-5-15(16(22)8-13)21(23,24)25/h3-8H,9-10H2,1-2H3,(H,27,28)
- InChIKey
- HWVNEWGKWRGSRK-UHFFFAOYSA-N
- SMILES
- C(O)(=O)COC1=CC=C(SCC2SC(C3=CC=C(C(F)(F)F)C(F)=C3)=NC=2C)C=C1C
화학적 성질
Light Yellow Solid
안전 및 규제
안전 정보는 참고용이며, 공급업체의 물질안전보건자료(SDS), 관련 법규 및 전문가 평가를 대체하지 않습니다.
안전 데이터
- wgk
- 3
- HS 번호
- 38220090
- 스토리지 클래스
- 11 - Combustible Solids
화학 및 산업
응용 분야
개요GW0742 is a PPARδ/β agonist very similar in molecular structure to GW501516 (Cardarine) — with the exception of one atom. It is often mentioned in comparison with Cardarine. This drug is mostly used by athletes to improve their stamina. The fat affecting properties of GW0742 also make it a good promoter of energy in the body. Additionally, this drug helps increase the oxidative abilities of your body muscles.
용도GW0742 is a small molecule agonist of the human Peroxisome Proliferator-Activated Recept δ (PPAR δ). It shows an EC50 of 1.1 nM against PPAR δ with 100-fold selectivity over the other human subtypes.
상·하류 제품 정보
상류 원료
공급사100 곳
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
湖南韵邦生物科技股份有限公司0731-88532326 13319508186 · [email protected]
南通飞宇生物科技有限公司0513-68819626 15152877458 · [email protected]
陕西缔都新材料有限公司81124267 17392282731 · [email protected]
武汉英诺医药科技有限公司+86-027-59232304 15387063101 · [email protected]
武汉敬康恩生物医药科技有限公司13720134139 086-15871494362 13720134139 · [email protected]
河南赢创生物科技有限公司16650615803 · [email protected]
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