Methylumbelliferone → (+/-)-cis-7-Methoxy-1,2,3,3a,4,9b-hexahydro-[1]-benzopyrano[3,4-c]pyrrole

참여 물질

역할	이름	HCID	투입량
반응물	Methylumbelliferone	HCID 10748	—
반응물	Benzyl(methoxymethyl)((trimethylsilyl)methyl)amine	HCID 353442	—
생성물	(+/-)-cis-7-Methoxy-1,2,3,3a,4,9b-hexahydro-[1]-benzopyrano[3,4-c]pyrrole	HCID 21309105	—

반응 단계

From 7-methoxycoumarin and N-methoxymethyl-N-trimethylsilylmethyl-benzylamine in an analogous manner as described in Examples 1A-C: 1H NMR (300 MHz, CDCl3), δ 1.92 (br s, 1H), 2.60 (m, 1H), 2.81 (m, 2H), 3.17 (q, 1H), 3.29 (dd, 1H), 3,40 (dd, 1H), 3.77 (s, 3H), 3.78 (t, 1H), 4.10 (dd, 1H), 6.43 (d, 1H), 6.52 (dd, 1H), 7.03 (d, 1H).

출처 및 근거

DOI	10.6084/m9.figshare.5104873.v1
특허 번호	US06046207
출처 데이터셋	uspto-grants-2000_04
ORD ID	ord-88d58bf5896c40ebacf070990c56b42d
출처 메모	uspto-grants-2000_04