6-Chloroindole → 6-Chloro-3-(1,2,3,6-tetrahydro-1,3-dimethyl-4-pyridinyl)-1H-indole

HRID 1003554노트

반응식

HRID 1003554 반응식
[Cl:1][C:2]1[CH:10]=[C:9]2[C:5]([CH:6]=[CH:7][NH:8]2)=[CH:4][CH:3]=1.[CH3:11][N:12]1[CH2:17][CH2:16][C:15](=O)[CH:14]([CH3:19])[CH2:13]1>>[Cl:1][C:2]1[CH:10]=[C:9]2[C:5]([C:6]([C:15]3[CH:14]([CH3:19])[CH2:13][N:12]([CH3:11])[CH2:17][CH:16]=3)=[CH:7][NH:8]2)=[CH:4][CH:3]=1

참가 물질

3

반응물 2

HCID 871116-ChloroindoleHCID 1073111,3-Dimethyl-4-piperidone

생성물 1

HCID 187972006-Chloro-3-(1,2,3,6-tetrahydro-1,3-dimethyl-4-pyridinyl)-1H-indole수율 63%

실험 절차

Beginning with 0.97 gm (6.4 mMol) 6-chloro-1H-indole and 1.6 gm (13.0 mMol) 1,3-dimethyl-4-piperidone, 1.05 gm (63%) of the title compound were recovered as a crystalline solid.

출처 및 근거

ORD 기록
ord-677fe81f51de4c14aa3981b7c1a5dd15
출처 데이터셋
uspto-grants-2000_04
특허 번호
US06046215

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