Piperonylamine → 6,7-dichloro-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole

HRID 1003567

반응식

HRID 1003567 반응식
[Cl:1][C:2]1[C:10]([Cl:11])=[C:9]2[C:5]([CH:6]=[CH:7][NH:8]2)=[CH:4][CH:3]=1.O.Cl.[NH:14]1[CH2:19][CH2:18][C:17](=O)[CH2:16][CH2:15]1>>[Cl:1][C:2]1[C:10]([Cl:11])=[C:9]2[C:5]([C:6]([C:17]3[CH2:18][CH2:19][NH:14][CH2:15][CH:16]=3)=[CH:7][NH:8]2)=[CH:4][CH:3]=1

참가 물질

3

반응물 2

HCID 2723901PiperonylamineHCID 122728026,7-dichloro-1H-indole

생성물 1

HCID 185459816,7-dichloro-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole수율 89.8%

실험 절차

Beginning with 1.4 gm (7.5 mMol) 6,7-dichloro-1H-indole and 2.3 gm (15.0 mMol) 4-piperidone hydrochloride monohydrate, 1.8 gm (89%) of the title compound were recovered as a white solid.

출처 및 근거

ORD 기록
ord-9491ec2c6c5e4890a79722fceaef756a
출처 데이터셋
uspto-grants-2000_04
특허 번호
US06046215

연결된 노트

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