Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Acetyl chloride → N-Methyl-phenylglycine methyl ester hydrochloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Acetyl chloride | HCID 6367 | — |
| 반응물 | N-Methyl-N-phenyl-glycine | HCID 420843 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | N-Methyl-phenylglycine methyl ester hydrochloride | HCID 70291077 | 94% |
반응 단계
Prepared by Method A of Example 19 but using N-methyl-phenylglycine (prepared in turn from 2-chlorophenylacetic acid and methylamine) (3.5 g) methanol (20 ml) and acetyl chloride (40 ml) over 48 hours. The title compound was obtained in 94% yield, after trituration with methanol, as a white solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06048852 |
| 출처 데이터셋 | uspto-grants-2000_04 |
| ORD ID | ord-3f0ae84401de4753b2d31985f3ef5bd9 |
| 출처 메모 | uspto-grants-2000_04 |