1-[4-[(4-Fluorophenyl)methyl]phenyl]piperazine → (E)-1-[4-(4-fluorophenyl)methylphenyl]-4-[3-(4-fluorophenyl)-2-propenyl]piperazine

HRID 1004136노트

반응식

HRID 1004136 반응식
[F:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][C:9]2[CH:14]=[CH:13][C:12]([N:15]3[CH2:20][CH2:19][NH:18][CH2:17][CH2:16]3)=[CH:11][CH:10]=2)=[CH:4][CH:3]=1.[F:21][C:22]1[CH:31]=[CH:30][C:25]([CH:26]=[CH:27][CH2:28]Br)=[CH:24][CH:23]=1>>[F:1][C:2]1[CH:3]=[CH:4][C:5]([CH2:8][C:9]2[CH:14]=[CH:13][C:12]([N:15]3[CH2:16][CH2:17][N:18]([CH2:28]/[CH:27]=[CH:26]/[C:25]4[CH:30]=[CH:31][C:22]([F:21])=[CH:23][CH:24]=4)[CH2:19][CH2:20]3)=[CH:11][CH:10]=2)=[CH:6][CH:7]=1

참가 물질

3

실험 절차

The same procedure was followed as in Example 11 using the compound (10) synthesized in Example 3 and 4-fluorocinnamyl bromide to produce the above.

후처리

  1. customto produce the above

출처 및 근거

ORD 기록
ord-00d91873a4fb4068a874962fe11dadf0
출처 데이터셋
uspto-grants-2000_04
특허 번호
US06048876

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