2-(Bromomethyl)-2-phenyl-1,3-dioxolane → 2-[4-(4-Phenoxyphenyl)piperidin-1-yl]methyl-2-phenyl-1,3-dioxolane

HRID 1004142

반응식

HRID 1004142 반응식
OC1C=CC(/C=C/C[N:11]2[CH2:16][CH2:15][CH:14]([C:17]3[CH:22]=[CH:21][C:20]([O:23][C:24]4[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=4)=[CH:19][CH:18]=3)[CH2:13][CH2:12]2)=CC=1OC.Br[CH2:33][C:34]1([C:39]2[CH:44]=[CH:43][CH:42]=[CH:41][CH:40]=2)[O:38][CH2:37][CH2:36][O:35]1>>[O:23]([C:20]1[CH:21]=[CH:22][C:17]([CH:14]2[CH2:15][CH2:16][N:11]([CH2:33][C:34]3([C:39]4[CH:44]=[CH:43][CH:42]=[CH:41][CH:40]=4)[O:38][CH2:37][CH2:36][O:35]3)[CH2:12][CH2:13]2)=[CH:18][CH:19]=1)[C:24]1[CH:25]=[CH:26][CH:27]=[CH:28][CH:29]=1

참가 물질

3

반응물 2

HCID 2915742-(Bromomethyl)-2-phenyl-1,3-dioxolaneHCID 18412177(E)-1-[3-(4-hydroxy-3-methoxyphenyl)-2-propenyl]-4-(4-phenoxyphenyl)piperidine

생성물 1

HCID 187944852-[4-(4-Phenoxyphenyl)piperidin-1-yl]methyl-2-phenyl-1,3-dioxolane

실험 절차

The same procedure was followed as in Example 11 using the compound (9) synthesized in Example 2 and 2-bromomethyl-2-phenyl-1,3-dioxolane to produce the above.

후처리

  1. customto produce the above

출처 및 근거

ORD 기록
ord-6dfaaa1d89d0495096c541549be929e2
출처 데이터셋
uspto-grants-2000_04
특허 번호
US06048876

연결된 노트

불러오는 중…