Chlorotrimethylsilane → HCID 18670031, 화합물

HRID 1004854노트

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HRID 1004854 반응식
[CH:1]1([C:10]([CH:13]2[C:21]3[C:16](=[CH:17][CH:18]=[CH:19][CH:20]=3)[CH:15]=[CH:14]2)([CH3:12])[CH3:11])[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH:3]=[CH:2]1.C([Li])CCC.C1(C(C2C3C(=CC=CC=3)C=C2)(C)C)C2C(=CC=CC=2)C=C1.[Li].[Li].[Si:50](Cl)([CH3:53])([CH3:52])[CH3:51]>CCOCC.CCCCC>[CH3:51][Si:50]([CH3:53])([CH3:52])[C:15]1[C:16]2[C:21](=[CH:20][CH:19]=[CH:18][CH:17]=2)[CH:13]([C:10]([CH:1]2[C:9]3[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=3)[C:3]([Si:50]([CH3:53])([CH3:52])[CH3:51])=[CH:2]2)([CH3:11])[CH3:12])[CH:14]=1

참가 물질

7

반응물 4

HCID 6397ChlorotrimethylsilaneHCID 117806711H-Indene, (1-methylethylidene)bis-HCID 69536615HCID 69536615, 화합물HCID 178418339Butyllithium

생성물 1

HCID 18670031HCID 18670031, 화합물

시약·촉매·용매 2

HCID 3283Diethyl Ether용매2회HCID 8003Pentane용매

실험 절차

5.45 g (20 mmol) of 2,2-bis(indenyl)propane was dissolved in 100 ml of ether. The solution thus obtained was taken to -20° C., and 22 ml of a 2.0 M solution of n-butyl-lithium in pentane was added, thus giving a suspension of dilithium-2,2-(indenyl)propane. 8.77 g (30.85 mmol) of dilithium 2,2-bis(indenyl)propane was dissolved in 100 ml of ether, and 10 ml of Me3SiCl (excess) was added at a temperature of -40° C. The resulting mixture was allowed to return to room temperature. The organic phase was then separated off, the solvent removed and the product dried in vacuo.

후처리

  1. customThe solution thus obtained
  2. customwas taken to -20° C.
  3. customthus giving
  4. customto return to room temperature
  5. customThe organic phase was then separated off
  6. customthe solvent removed
  7. customthe product dried in vacuo

출처 및 근거

ORD 기록
ord-5d87ddfe82c7409db10da039d511a4f7
출처 데이터셋
uspto-grants-2000_04
특허 번호
US06051728

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