HCID 21706478, 화합물 → HCID 21706521, 화합물
반응식
[CH3:1][O:2][C:3]1[CH:21]=[CH:20][C:6]([CH2:7][N:8]2[CH:13]=[CH:12][C:11]([CH:14]=[CH2:15])=[C:10]([N+:16]([O-])=O)[C:9]2=[O:19])=[CH:5][CH:4]=1>C(O)C.[Pd]>[NH2:16][C:10]1[C:9](=[O:19])[N:8]([CH2:7][C:6]2[CH:5]=[CH:4][C:3]([O:2][CH3:1])=[CH:21][CH:20]=2)[CH:13]=[CH:12][C:11]=1[CH2:14][CH3:15]참가 물질
4
실험 절차
A mixture of 1-(4-methoxybenzyl)-4-vinyl-3-nitro-2-pyridone (0.21 g, 0.73 mmol) in ethanol (30 mL) with 10% Pd/C (0.26 g) was hydrogenated at 40 psi in a Parr apparatus for 4 hours. The catalyst was removed by filtration and the solvent was evaporated to give 3-amino-1-(4-methoxybenzyl)-4-ethyl-2-pyridone (0.17 g, 0.56 mmol, 76%).
후처리
- customThe catalyst was removed by filtration
- customthe solvent was evaporated
출처 및 근거
- ORD 기록
- ord-27010cbcfab64663b94cab7e2752e978
- 출처 데이터셋
- uspto-grants-2000_04
- 특허 번호
- US06054470
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