Iodine → HCID 21706514, 화합물

HRID 1005408

반응식

HRID 1005408 반응식
[CH3:1][C:2]1[CH:7]=[CH:6][NH:5][C:4](=[O:8])[C:3]=1[N+:9]([O-:11])=[O:10].II.[I:14]([O-])(=O)=O.[Na+].O>C(O)(=O)C.S(=O)(=O)(O)O>[I:14][C:7]1[C:2]([CH3:1])=[C:3]([N+:9]([O-:11])=[O:10])[C:4](=[O:8])[NH:5][CH:6]=1

참가 물질

7

반응물 4

HCID 807IodineHCID 962WaterHCID 3453702-Hydroxy-4-methyl-3-nitropyridineHCID 23675764Sodium Iodate

생성물 1

HCID 21706514HCID 21706514, 화합물

시약·촉매·용매 2

HCID 176Acetic Acid용매HCID 1118Sulfuric Acid용매

반응 조건

온도
75 °C

실험 절차

To a solution of 4-methyl-3-nitro-2-pyridone (2.00 g, 13 mmol) in acetic acid (12 mL) and concentrated sulfuric acid (1.6 mL) was added iodine (1.32 g) and sodium iodate (0.55 g). The mixture was heated at 75° C. for 2.5 hours and then stirred at rt overnight. Water (100 mL) was added, and the precipitated 5-iodo-4-methyl-3-nitro-2-pyridone was collected by filtration (2.97 g, 82%).

후처리

  1. filtrationthe precipitated 5-iodo-4-methyl-3-nitro-2-pyridone was collected by filtration (2.97 g, 82%)

출처 및 근거

ORD 기록
ord-4e5a26406f1f46738924a78380e55939
출처 데이터셋
uspto-grants-2000_04
특허 번호
US06054470

연결된 노트

불러오는 중…