Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1,1-Dimethoxycyclohexane → 5-(3,5-Dimethylphenylthio)-4-isopropyl-1-[2-(1-methoxycyclohexyloxy)ethoxymethyl)-2-methyl-1H-imidazole
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1,1-Dimethoxycyclohexane | HCID 13616 | — |
| 반응물 | 2-[5-(3,5-Dimethyl-phenylsulfanyl)-4-isopropyl-2-methyl-imidazol-1-ylmethoxy]-ethanol | HCID 478180 | — |
| 생성물 | 5-(3,5-Dimethylphenylthio)-4-isopropyl-1-[2-(1-methoxycyclohexyloxy)ethoxymethyl)-2-methyl-1H-imidazole | HCID 15887185 | 62.7% |
반응 단계
The compound 1 (33.4 mg, 0.1 mmol) was converted to the acetal with 1,1-dimethoxycyclohexane (144 mg, 1.00 mmol) in the same manner as the example 1 to give the compound 3 (28 mg, 60 %). Rf 0.57 (Al2O3 60, Type E, 2:1 hexane -EtOAc).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06054591 |
| 출처 데이터셋 | uspto-grants-2000_04 |
| ORD ID | ord-bba29cb80c604331ba80ef68910fa405 |
| 출처 메모 | uspto-grants-2000_04 |