Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Carbamate → [5-(3,5-dichlorophenyl)sulfanyl-4-isopropyl-1-(4-pyridylmethyl)imidazol-2-yl]methyl N-octanoylcarbamate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Carbamate | HCID 276 | — |
| 반응물 | {5-[(3,5-Dichlorophenyl)sulfanyl]-4-isopropyl-1-((pyridin-4-YL)methyl)imidazol-2-YL}methanol | HCID 9844329 | — |
| 반응물 | Octanoyl isocyanate | HCID 18791988 | — |
| 생성물 | [5-(3,5-dichlorophenyl)sulfanyl-4-isopropyl-1-(4-pyridylmethyl)imidazol-2-yl]methyl N-octanoylcarbamate | HCID 478193 | 56% |
반응 단계
The compound 89 (101-1048 (816 mg, 2.00 mmol) was converted to the carbamate with octanoyl isocyanate (5 eq.) in the same manner as the example 66 to give the compound 91 (650 mg, 56%) as crystals. Mp. 139-141° C. Rf 0.34 (EtOAc).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06054591 |
| 출처 데이터셋 | uspto-grants-2000_04 |
| ORD ID | ord-e73b23b2ac694e30b105f27a1b58e5b1 |
| 출처 메모 | uspto-grants-2000_04 |