Ammonia → 6-Amino-3-methoxy-2-pyrazinecarboxamide
반응식
[NH2:1][C:2]1[N:7]=[C:6]([C:8](OC)=[O:9])[C:5]([O:12][CH3:13])=[N:4][CH:3]=1.[NH3:14]>CO>[NH2:1][C:2]1[N:7]=[C:6]([C:8]([NH2:14])=[O:9])[C:5]([O:12][CH3:13])=[N:4][CH:3]=1참가 물질
4
실험 절차
In 70 mL of methanol is dissolved 3.50 g of methyl 6-amino-3-methoxy-2-pyrazinecarboxylate. Gaseous ammonia is introduced to saturate the solution with ammonia. The solution is stirred at ambient temperature for 14 hours. The solvent is distilled off from the reaction mixture under reduced pressure to obtain 3.1 g of 6-amino-3-methoxy-2-pyrazinecarboxamide.
후처리
- concentrationto saturate the solution with ammonia
- distillationThe solvent is distilled off from the reaction mixture under reduced pressure
출처 및 근거
- ORD 기록
- ord-8945073da1d74c91b7401f03e7d09e37
- 출처 데이터셋
- uspto-grants-2004_09
- 특허 번호
- US06787544B2
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