Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Water → 4-[4-(O-Benzyloximino)cyclohexylamino]-3-methoxy-2-methylpyridine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Water | HCID 962 | — |
| 반응물 | O-Benzylhydroxylamine | HCID 102313 | — |
| 반응물 | 4-(4-Oxocyclohexylamino)-3-methoxy-2-methylpyridine | HCID 19693951 | — |
| 반응물 | Ethylacetate methanol | HCID 21584119 | — |
| 용매 | Toluene | HCID 1140 | — |
| 생성물 | 4-[4-(O-Benzyloximino)cyclohexylamino]-3-methoxy-2-methylpyridine | HCID 19693973 | — |
반응 단계
2 g of 4-(4-oxocyclohexylamino)-3-methoxy-2-methylpyridine and 1.2 g O-benzylhydroxylamine are boiled in toluene in a water separator until liberation of water has ended. The product is isolated by column chromatography (ethyl acetate/methanol 9:1; silica gel). 1.8 g=53%
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05723450 |
| 출처 데이터셋 | uspto-grants-1998_03 |
| ORD ID | ord-7b74a27dcc2940b5b3a704ddbd2de98d |
| 출처 메모 | uspto-grants-1998_03 |