참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Methanol | HCID 887 | — |
| 반응물 | Thionyl Chloride | HCID 24386 | — |
| 반응물 | Pipecolic acid, (-)- | HCID 439227 | — |
| 생성물 | methyl (2S)-piperidine-2-carboxylate hydrochloride | HCID 13246232 | — |
반응 단계
Thionyl chloride (0.58 ml) was added dropwise to a solution of L-pipecolinic acid (450 mg) in methanol at room temperature. The reaction mixture was stirred at 55° C. for 2 hours. The whole mixture was evaporated under reduced pressure to give (2S)-piperidine-2-carboxylic acid methyl ester hydrochloride as a colorless oil.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US06787543B2 |
|---|
| 출처 데이터셋 | uspto-grants-2004_09 |
|---|
| ORD ID | ord-6a6deb3a16944022b212e5e35fcbc918 |
|---|
| 출처 메모 | uspto-grants-2004_09 |
|---|
