Tetrahydrofuran → N-{4-chloro-5-[(2-{[(4-ethylpiperazin-1-yl)acetyl]amino}[1,3]thiazolo[5,4-b]pyridin-5-yl)oxy]-2-fluorophenyl}-3-(1-cyano-1-methylethyl)benzamide

HRID 100642

반응식

[CH2:45]([CH3:46])[N:47]1[CH2:48][CH2:49][NH:50][CH2:51][CH2:52]1.[CH3:38][CH2:39][N:40]([CH2:41][CH3:42])[CH2:43][CH3:44].[CH3:58][CH2:59][O:60][C:61](=[O:62])[CH3:63].[Cl:1][c:2]1[cH:3][c:4]([F:37])[c:5]([NH:23][C:24]([c:25]2[cH:26][c:27]([C:31]([CH3:32])([CH3:33])[C:34]#[N:35])[cH:28][cH:29][cH:30]2)=[O:36])[cH:6][c:7]1[O:8][c:9]1[cH:10][cH:11][c:12]2[c:13]([n:14]1)[s:15][c:16]([NH:18][C:19]([CH2:20][Cl:21])=[O:22])[n:17]2.[O:53]1[CH2:54][CH2:55][CH2:56][CH2:57]1>>[Cl:1][c:2]1[cH:3][c:4]([F:37])[c:5]([NH:23][C:24]([c:25]2[cH:26][c:27]([C:31]([CH3:32])([CH3:33])[C:34]#[N:35])[cH:28][cH:29][cH:30]2)=[O:36])[cH:6][c:7]1[O:8][c:9]1[cH:10][cH:11][c:12]2[c:13]([n:14]1)[s:15][c:16]([NH:18][C:19]([CH2:20][N:50]1[CH2:49][CH2:48][N:47]([CH2:45][CH3:46])[CH2:52][CH2:51]1)=[O:22])[n:17]2