5-Chloro-4-(chloromethyl)-1,2,3-thiadiazole → (2R)-2-[[2-amino-5-[(5-chloro-1,2,3-thiadiazol-4-yl)thio]thiazolo[4,5-d]pyrimidin-7-yl]amino]-1-propanol

HRID 1006516노트

반응식

HRID 1006516 반응식
[NH2:1][C:2]1[S:3][C:4]2[C:9]([NH:10][C@H:11]([CH3:14])[CH2:12][OH:13])=[N:8][C:7]([SH:15])=[N:6][C:5]=2[N:16]=1.[Cl:17][C:18]1[S:22][N:21]=[N:20][C:19]=1CCl>>[NH2:1][C:2]1[S:3][C:4]2[C:9]([NH:10][C@H:11]([CH3:14])[CH2:12][OH:13])=[N:8][C:7]([S:15][C:19]3[N:20]=[N:21][S:22][C:18]=3[Cl:17])=[N:6][C:5]=2[N:16]=1

참가 물질

3

반응물 2

HCID 27974905-Chloro-4-(chloromethyl)-1,2,3-thiadiazoleHCID 178461804HCID 178461804, 화합물

생성물 1

HCID 86635808(2R)-2-[[2-amino-5-[(5-chloro-1,2,3-thiadiazol-4-yl)thio]thiazolo[4,5-d]pyrimidin-7-yl]amino]-1-propanol

실험 절차

Prepared by the method of example 32 step c), using the product of example 32 step b) and 5-chloro-4-(chloromethyl)-1,2,3-thiadiazole.

후처리

  1. customPrepared by the method of example 32 step c),

출처 및 근거

ORD 기록
ord-655e284de92748c7b3bab74e7e9b515e
출처 데이터셋
uspto-grants-2004_09
특허 번호
US06790850B1

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