Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Hydroxy-3-methoxybenzonitrile → 3,4-Dihydroxybenzonitrile
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Hydroxy-3-methoxybenzonitrile | HCID 78135 | — |
| 반응물 | Lithium Bromide | HCID 82050 | — |
| 반응물 | 3,4-Diethoxybenzonitrile | HCID 12946190 | — |
| 생성물 | 3,4-Dihydroxybenzonitrile | HCID 87065 | 79% |
반응 단계
The preparation was carried out according to the process of Example 2a except that 3,4-diethoxybenzonitrile was used as the starting material instead of 3-methoxy-4-hydroxybenzonitrile, and 2-fold of lithium bromide (162.6 g, 1.88 mole) were added to form the reaction mixture. 3,4-Dihydroxybenzonitrile was obtained as a white solid with a yield of 79% and a purity of greater than 92% as indicated by HPLC analysis.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06790977B2 |
| 출처 데이터셋 | uspto-grants-2004_09 |
| ORD ID | ord-59cb6a1788d04c77932ef7acef6dc074 |
| 출처 메모 | uspto-grants-2004_09 |