Methylamine → N,2-Dimethyl-3-pyridinecarboxamide
반응식
[CH3:1][C:2]1[N:12]=[CH:11][CH:10]=[CH:9][C:3]=1[C:4](OCC)=[O:5].[CH3:13][NH2:14]>CO>[CH3:1][C:2]1[N:12]=[CH:11][CH:10]=[CH:9][C:3]=1[C:4]([NH:14][CH3:13])=[O:5]참가 물질
4
반응 조건
- 온도
- 50 °C
실험 절차
To ethyl 2-methylnicotinate (24.2 g) was added a solution of 40% methylamine in methanol (150 ml), which was then heated in a sealed tube at 50° C. overnight. The reaction mixture was evaporated, to give the title compound as a pale yellow solid (20.781 g, yield; 95%).
후처리
- customThe reaction mixture was evaporated
출처 및 근거
- ORD 기록
- ord-5185a0c1e0ae4625a178ecb3812d55ed
- 출처 데이터셋
- uspto-grants-2004_09
- 특허 번호
- US06790844B2
반응 노트
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