Nitric Acid → 4,5-Diethoxy-2-nitro-phenylacetic acid

HRID 1007373노트

반응식

HRID 1007373 반응식
[CH2:1]([O:3][C:4]1[CH:5]=[C:6]([CH2:13][C:14]([OH:16])=[O:15])[CH:7]=[CH:8][C:9]=1[O:10][CH2:11][CH3:12])[CH3:2].[N+:17]([O-])([OH:19])=[O:18]>C(O)(=O)C>[CH2:11]([O:10][C:9]1[C:4]([O:3][CH2:1][CH3:2])=[CH:5][C:6]([CH2:13][C:14]([OH:16])=[O:15])=[C:7]([N+:17]([O-:19])=[O:18])[CH:8]=1)[CH3:12]

참가 물질

4

반응물 2

HCID 944Nitric AcidHCID 5798133,4-Diethoxyphenylacetic acid

생성물 1

HCID 47122074,5-Diethoxy-2-nitro-phenylacetic acid

시약·촉매·용매 1

HCID 176Acetic Acid용매

반응 조건

온도
40 °C

실험 절차

0.5 g of 3,4-diethoxy-phenylacetic acid are placed in 10 ml of acetic acid p.a. and 0.5 ml of 659 nitric acid are added dropwise, so that the internal temperature does not rise above 15° C. The mixture is then heated to 40° C. for 0.5 hours. After this time the solution is poured onto ice water and the precipitate formed is suction filtered. The product is washed with water and dried at 100° C.

후처리

  1. customdoes not rise above 15° C
  2. additionAfter this time the solution is poured onto ice water
  3. customthe precipitate formed
  4. filtrationfiltered
  5. washThe product is washed with water
  6. customdried at 100° C.

출처 및 근거

ORD 기록
ord-825ba08f992944b482b8b0ed44786f9f
출처 데이터셋
uspto-grants-2004_09
특허 번호
US06794395B1

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