Water → Bicyclo[2.2.1]heptane-2,3-diol

HRID 1007625

반응식

HRID 1007625 반응식
[O:1]1[CH:7]2[CH:2]1[CH:3]1[CH2:8][CH:6]2[CH2:5][CH2:4]1.O.S(=O)(=O)(O)[OH:11]>CC(C)=O>[OH:11][CH:2]1[CH:7]([OH:1])[CH:6]2[CH2:8][CH:3]1[CH2:4][CH2:5]2

참가 물질

5

반응물 3

HCID 962WaterHCID 1118Sulfuric AcidHCID 18463exo-2,3-Epoxynorbornane

생성물 1

HCID 85735Bicyclo[2.2.1]heptane-2,3-diol

시약·촉매·용매 1

HCID 180Acetone용매

실험 절차

Into a four-neck flask (200 ml) were fed 20.3 g (185 mmol) of 2,3-epoxynorbornane, 50 ml of water, 25 ml of acetone, and 50 μl of sulfuric acid, and the reaction mixture was refluxed at 40° C. for 6 hours. After complete reaction, an object compound was extracted with each 40 ml of diethylether five times, and the resultant extract was washed with saturated salt solution (braine), and was dried with sodium sulfate to obtain 2,3-dihydroxynorbornane.

후처리

  1. customInto a four-neck flask (200 ml) were fed
  2. customAfter complete reaction
  3. extractionan object compound was extracted with each 40 ml of diethylether five times
  4. extractionthe resultant extract
  5. washwas washed with saturated salt solution (braine)
  6. dry with materialwas dried with sodium sulfate

출처 및 근거

ORD 기록
ord-5d2bc6da749c4c62bd5f9b33b471649e
출처 데이터셋
uspto-grants-2004_09
특허 번호
US06794528B2

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