6-Phenyl-1,3-dihydro-indol-2-one → HCID 67282960, 화합물

HRID 1008164노트

반응식

HRID 1008164 반응식
[C:1]1([C:7]2[CH:15]=[C:14]3[C:10]([CH2:11][C:12](=[O:16])[NH:13]3)=[CH:9][CH:8]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH3:17][N:18]([CH3:33])[CH2:19][CH2:20][NH:21][C:22]([C:24]1[C:28]([CH3:29])=[C:27]([CH:30]=O)[NH:26][C:25]=1[CH3:32])=[O:23]>>[CH3:17][N:18]([CH3:33])[CH2:19][CH2:20][NH:21][C:22]([C:24]1[C:28]([CH3:29])=[C:27]([CH:30]=[C:11]2[C:10]3[C:14](=[CH:15][C:7]([C:1]4[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=4)=[CH:8][CH:9]=3)[NH:13][C:12]2=[O:16])[NH:26][C:25]=1[CH3:32])=[O:23]

참가 물질

3

반응물 2

HCID 105363846-Phenyl-1,3-dihydro-indol-2-oneHCID 54380946N-(2-(Dimethylamino)ethyl)-5-formyl-2,4-dimethyl-1H-pyrrole-3-carboxamide

생성물 1

HCID 67282960HCID 67282960, 화합물수율 37.9%

실험 절차

6-Phenyl-1,3-dihydroindol-2-one (0.17 g, 0.8 mmol) was condensed with 5-formyl-2,4-dimethyl-1H-pyrrole-3-carboxylic acid (2-dimethylaminoethyl)amide (0.2 g) to give 0.13 g (36%) of the title compound as a yellow-orange solid.

출처 및 근거

ORD 기록
ord-e8cba0ea26b14c799aceb554dc2e1019
출처 데이터셋
uspto-grants-2004_09
특허 번호
US06797725B2

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