2-Bromo-1-benzofuran → (S)-methyl 3-(benzofuran-2-yl)-2-(tert-butoxycarbonyl)propanoate

HRID 1009130

반응식

HRID 1009130 반응식
[C:1]([O:5][C:6]([C@H:8]([CH2:13]I)[C:9]([O:11][CH3:12])=[O:10])=[O:7])([CH3:4])([CH3:3])[CH3:2].Br[C:16]1[O:17][C:18]2[CH:24]=[CH:23][CH:22]=[CH:21][C:19]=2[CH:20]=1>>[O:17]1[C:18]2[CH:24]=[CH:23][CH:22]=[CH:21][C:19]=2[CH:20]=[C:16]1[CH2:13][C@H:8]([C:6]([O:5][C:1]([CH3:4])([CH3:3])[CH3:2])=[O:7])[C:9]([O:11][CH3:12])=[O:10]

참가 물질

3

반응물 2

HCID 27762642-Bromo-1-benzofuranHCID 86614124(R)-methyl2-(tert-butoxycarbonyl)-3-iodopropanoate

생성물 1

HCID 67270336(S)-methyl 3-(benzofuran-2-yl)-2-(tert-butoxycarbonyl)propanoate

실험 절차

The title compound was synthesized in a manner analogous to that described Example 475, using (R)-methyl 2-(tert-butoxycarbonyl)-3-iodopropanoate and 2-bromobenzofuran. (MS m/z: 220.1 (100%, M−99).

출처 및 근거

ORD 기록
ord-fb370dd91b654782ae878d757c41d2bd
출처 데이터셋
uspto-grants-2011_07
특허 번호
US07973047B2

연결된 노트

불러오는 중…