Water → 4-Bromo-2,6-dinitroaniline

HRID 1010650

반응식

HRID 1010650 반응식
[N+:1]([C:4]1[CH:10]=[CH:9][CH:8]=[C:7]([N+:11]([O-:13])=[O:12])[C:5]=1[NH2:6])([O-:3])=[O:2].[Br:14]Br.O>C(O)(=O)C>[Br:14][C:9]1[CH:10]=[C:4]([N+:1]([O-:3])=[O:2])[C:5]([NH2:6])=[C:7]([N+:11]([O-:13])=[O:12])[CH:8]=1

참가 물질

5

반응물 3

HCID 962WaterHCID 24408BromineHCID 690702,6-Dinitroaniline

생성물 1

HCID 37466084-Bromo-2,6-dinitroaniline수율 91%

시약·촉매·용매 1

HCID 176Acetic Acid용매

실험 절차

A stirred suspension of 2,6-dinitroaniline (5 g, 27.3 mmol) in glacial acetic acid (50 ml) was treated, dropwise, with bromine (1.5 ml, 30 mmol) and heated at 120° C. for 2 h. After cooling to ambient temperature, the resultant mixture was poured into water (500 ml). The precipitated solid was collected by filtration, washed with water and dried in vacuo to give 4-Bromo-2,6-dinitroaniline as a yellow solid (6.5 g, 91%).

후처리

  1. additionwas treated
  2. filtrationThe precipitated solid was collected by filtration
  3. washwashed with water
  4. customdried in vacuo

출처 및 근거

ORD 기록
ord-ce6a83acc53f406d80b5e92c1457f44d
출처 데이터셋
uspto-grants-2011_07
특허 번호
US07977340B2

연결된 노트

불러오는 중…