3-(4-Bromobutyl)oxolane → 2-(Butyloxy)-8-(methyloxy)-9-[4-(tetrahydro-3-furanyl)butyl]-9H-Purin-6-amine
반응식
FC(F)(F)C(O)=O.[CH2:8]([O:12][C:13]1[NH:14][C:15]([NH2:24])=[C:16]2[C:20]([N:21]=1)=[N:19][C:18]([O:22][CH3:23])=[N:17]2)[CH2:9][CH2:10][CH3:11].Br[CH2:26][CH2:27][CH2:28][CH2:29][CH:30]1[CH2:34][CH2:33][O:32][CH2:31]1>>[CH2:8]([O:12][C:13]1[N:21]=[C:20]2[C:16]([N:17]=[C:18]([O:22][CH3:23])[N:19]2[CH2:26][CH2:27][CH2:28][CH2:29][CH:30]2[CH2:34][CH2:33][O:32][CH2:31]2)=[C:15]([NH2:24])[N:14]=1)[CH2:9][CH2:10][CH3:11]참가 물질
3
실험 절차
Prepared similarly to Intermediate 216 from 2-(butyloxy)-8-(methyloxy)-1H-purin-6-amine trifluoroacetate and 3-(4-bromobutyl)tetrahydrofuran.
출처 및 근거
- ORD 기록
- ord-dcfb20b0eaf0492ca42732f1c7b0cd09
- 출처 데이터셋
- uspto-grants-2011_07
- 특허 번호
- US07977344B2
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