2-(2-Bromoethyl)oxane → HCID 57699807, 화합물

반응식

FC(F)(F)C(O)=O.[CH3:8][C@H:9]([O:13][C:14]1[NH:15][C:16]([NH2:25])=[C:17]2[C:21]([N:22]=1)=[N:20][C:19]([O:23][CH3:24])=[N:18]2)[CH2:10][CH2:11][CH3:12].Br[CH2:27][CH2:28][CH:29]1[CH2:34][CH2:33][CH2:32][CH2:31][O:30]1>>[CH3:8][C@H:9]([O:13][C:14]1[N:22]=[C:21]2[C:17]([N:18]=[C:19]([O:23][CH3:24])[N:20]2[CH2:27][CH2:28][CH:29]2[CH2:34][CH2:33][CH2:32][CH2:31][O:30]2)=[C:16]([NH2:25])[N:15]=1)[CH2:10][CH2:11][CH3:12]

참가 물질

반응물 2

HCID 127915862-(2-Bromoethyl)oxane

HCID 178448285HCID 178448285, 화합물

생성물 1

HCID 57699807HCID 57699807, 화합물

실험 절차

Prepared similarly to Intermediate 243 from 2-{[(1S)-1-methylbutyl]oxy}-8-(methyloxy)-1H-purin-6-amine trifluoroacetate and 2-(2-bromoethyl)tetrahydro-2H-pyran.

출처 및 근거

ORD 기록: ord-17946a347a2d460cba4dd31620bd2963
출처 데이터셋: uspto-grants-2011_07
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07977344B2

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