1050496-83-7 → HCID 57699619, 화합물

반응식

FC(F)(F)C(O)=O.[CH3:8][C@H:9]([O:13][C:14]1[NH:15][C:16]([NH2:25])=[C:17]2[C:21]([N:22]=1)=[N:20][C:19]([O:23][CH3:24])=[N:18]2)[CH2:10][CH2:11][CH3:12].Br[CH2:27][CH2:28][CH:29]1[CH2:34][CH2:33][O:32][C:31]([CH3:36])([CH3:35])[CH2:30]1>>[CH3:35][C:31]1([CH3:36])[CH2:30][CH:29]([CH2:28][CH2:27][N:20]2[C:19]([O:23][CH3:24])=[N:18][C:17]3[C:21]2=[N:22][C:14]([O:13][C@@H:9]([CH3:8])[CH2:10][CH2:11][CH3:12])=[N:15][C:16]=3[NH2:25])[CH2:34][CH2:33][O:32]1

참가 물질

반응물 2

HCID 576997121050496-83-7

HCID 178448285HCID 178448285, 화합물

생성물 1

HCID 57699619HCID 57699619, 화합물

실험 절차

Prepared similarly to Intermediate 243 from 2-{[(1S)-1-methylbutyl]oxy}-8-(methyloxy)-1H-purin-6-amine trifluoroacetate and 4-(2-bromoethyl)-2,2-dimethyltetrahydro-2H-pyran.

출처 및 근거

ORD 기록: ord-d07cc8ff2a734ec3b11571a1e65931d4
출처 데이터셋: uspto-grants-2011_07
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07977344B2

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