Lactic Acid → Isonicotinic Acid Amide Lactic Acid

HRID 10119

반응식

HRID 10119 반응식
C1SC(NC(N)=N)=NC=1CSCCC(NS(N)(=O)=O)=N.[C:21]([NH2:29])(=[O:28])[C:22]1[CH:27]=[CH:26][N:25]=[CH:24][CH:23]=1.[C:30]([OH:35])(=[O:34])[CH:31]([CH3:33])[OH:32]>O>[C:21]([NH2:29])(=[O:28])[C:22]1[CH:27]=[CH:26][N:25]=[CH:24][CH:23]=1.[C:30]([OH:35])(=[O:34])[CH:31]([CH3:33])[OH:32]

참가 물질

5

반응물 3

HCID 612Lactic AcidHCID 15074IsonicotinamideHCID 178418935HCID 178418935, 화합물2회

생성물 1

HCID 86591738Isonicotinic Acid Amide Lactic Acid

시약·촉매·용매 1

HCID 962Water용매2회

실험 절차

To 1 g of famotidine and 5 g of isonicotinic acid amide were added about 80 ml of water for injection and 2.20 ml of a 100 mg/ml aqueous lactic acid solution, followed by stirring to dissolve them. After complete dissolution of famotidine, water for injection was added to make the total volume 100 ml, whereby an injection solution having a pH of 6.2 and a kinematic viscosity at room temperature of 0.95 centistokes was obtained.

후처리

  1. dissolutionto dissolve them
  2. additionwas added
  3. customa kinematic viscosity at room temperature of 0.95 centistokes was obtained

출처 및 근거

ORD 기록
ord-6961669486c8494bb2c3a3bdd60048e7
출처 데이터셋
uspto-grants-2006_08
특허 번호
US07094414B2

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