Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Benzo[b]furan-2-boronic acid → [1-(3-Benzofuran-2-yl-phenyl)-3,5-dimethyl-1H-pyrazol-4-yl]-(3-diethylamino-pyrrolidin-1-yl)-methanone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Benzo[b]furan-2-boronic acid | HCID 2776266 | — |
| 반응물 | [1-(3-Bromo-phenyl)-3,5-dimethyl-1H-pyrazol-4-yl]-(3-diethylamino-pyrrolidin-1-yl)-methanone | HCID 67313795 | — |
| 생성물 | [1-(3-Benzofuran-2-yl-phenyl)-3,5-dimethyl-1H-pyrazol-4-yl]-(3-diethylamino-pyrrolidin-1-yl)-methanone | HCID 67314630 | 68% |
반응 단계
In analogy to the procedure described in Example 14C], [1-(3-bromo-phenyl)-3,5-dimethyl-1H-pyrazol-4-yl]-(3-diethylamino-pyrrolidin-1-yl)-methanone and benzo[b]furan-2-boronic acid gave the title compound in 68% yield as light brown foam. MS: 457.3 (MH+).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07977358B2 |
| 출처 데이터셋 | uspto-grants-2011_07 |
| ORD ID | ord-485608d19c7848f1abe7955b6df2068f |
| 출처 메모 | uspto-grants-2011_07 |