Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
(3-Diethylamino-pyrrolidin-1-yl)-[3,5-dimethyl-1-[3-(3-methyl-but-1-ynyl)-phenyl]-1H-pyrazol-4-yl}-methanone → (3-Diethylamino-pyrrolidin-1-yl)-[3,5-dimethyl-1-[3-(3-methyl-butyl)-phenyl]-1H-pyrazol-4-yl}-methanone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | (3-Diethylamino-pyrrolidin-1-yl)-[3,5-dimethyl-1-[3-(3-methyl-but-1-ynyl)-phenyl]-1H-pyrazol-4-yl}-methanone | HCID 57554954 | — |
| 촉매 | Platinum dioxide monohydrate | HCID 11139377 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | (3-Diethylamino-pyrrolidin-1-yl)-[3,5-dimethyl-1-[3-(3-methyl-butyl)-phenyl]-1H-pyrazol-4-yl}-methanone | HCID 57555039 | 93% |
반응 단계
A suspension of 0.041 g (0.10 mmol) of (3-diethylamino-pyrrolidin-1-yl)-{3,5-dimethyl-1-[3-(3-methyl-but-1-ynyl)-phenyl]-1H-pyrazol-4-yl}-methanone (Example 361) and 6 mg of platinum(IV) oxide hydrate in 0.2 ml of EtOH was stirred under hydrogen atmosphere 17 h at RT and 1 atm. The suspension was filtered and evaporated to give 0.038 g (93%) of the titled compound as colorless viscous oil. MS: 411.2 (MH+).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07977358B2 |
| 출처 데이터셋 | uspto-grants-2011_07 |
| ORD ID | ord-6b66d41878584d2485f559ec90ee3ee0 |
| 출처 메모 | uspto-grants-2011_07 |