Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
m-Chlorophenylhydrazine hydrochloride → 1-(3-chlorophenyl)-3,5-dimethyl-1H-pyrazole-4-carboxylic acid ethyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | m-Chlorophenylhydrazine hydrochloride | HCID 75331 | — |
| 반응물 | Ethyl 2-acetylacetoacetate | HCID 79063 | — |
| 생성물 | 1-(3-chlorophenyl)-3,5-dimethyl-1H-pyrazole-4-carboxylic acid ethyl ester | HCID 9965472 | 58% |
반응 단계
In analogy to the procedure described in Example 38A], 3-chlorophenylhydrazine hydrochloride and ethyl diacetoacetate gave the title compound after purification by flash column chromatography (n-heptane:EtOAc 9:1-1:1) in 58% yield as light yellow solid. MS: 279.0 (MH+, 1 Cl).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07977358B2 |
| 출처 데이터셋 | uspto-grants-2011_07 |
| ORD ID | ord-59f743d999b741b3a2f97438755cde7a |
| 출처 메모 | uspto-grants-2011_07 |