Ethyl 3-cyclopropyl-3-oxopropanoate → 2-Cyclopropanecarbonyl-3-oxo-3-pyrimidin-5-yl-propionic acid ethyl ester
반응식
[CH2:1]([O:3][C:4](=[O:11])[CH2:5][C:6]([CH:8]1[CH2:10][CH2:9]1)=[O:7])[CH3:2].[N:12]1[CH:17]=[C:16]([C:18](Cl)=[O:19])[CH:15]=[N:14][CH:13]=1>>[CH2:1]([O:3][C:4](=[O:11])[CH:5]([C:6]([CH:8]1[CH2:10][CH2:9]1)=[O:7])[C:18](=[O:19])[C:16]1[CH:17]=[N:12][CH:13]=[N:14][CH:15]=1)[CH3:2]참가 물질
3
실험 절차
In analogy to the procedure described in Example 162A], 3-cyclopropyl-3-oxo-propionic acid ethyl ester and pyrimidine-5-carbonyl chloride gave the title compound as a yellow oil (40%). MS: 261.3 (M−H−).
출처 및 근거
- ORD 기록
- ord-3d9bef452497492ca73ccdc5cee595de
- 출처 데이터셋
- uspto-grants-2011_07
- 특허 번호
- US07977358B2
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