Hydrazinium chloride → 5-cyclopropyl-3-pyrimidin-5-yl-1H-pyrazole-4-carboxylic acid ethyl ester

HRID 1011994노트

반응식

HRID 1011994 반응식
[CH2:1]([O:3][C:4](=[O:19])[CH:5]([C:14]([CH:16]1[CH2:18][CH2:17]1)=O)[C:6](=O)[C:7]1[CH:8]=[N:9][CH:10]=[N:11][CH:12]=1)[CH3:2].Cl.[NH2:21][NH2:22]>>[CH2:1]([O:3][C:4]([C:5]1[C:6]([C:7]2[CH:8]=[N:9][CH:10]=[N:11][CH:12]=2)=[N:21][NH:22][C:14]=1[CH:16]1[CH2:18][CH2:17]1)=[O:19])[CH3:2]

참가 물질

3

실험 절차

In analogy to the procedure described in Example 162B], 2-cyclopropanecarbonyl-3-oxo-3-pyrimidin-5-yl-propionic acid ethyl ester and hydrazine.hydrochloride gave the title compound as white solid (39%). MS: 259.1 (MH+).

출처 및 근거

ORD 기록
ord-ed9e3b65eb7543a28052ccc672f76804
출처 데이터셋
uspto-grants-2011_07
특허 번호
US07977358B2

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