3-oxo-3,4-dihydro-2H-1,4-benzoxazine-6-carbaldehyde → HCID 178489236, 화합물

HRID 1012921

반응식

HRID 1012921 반응식
[CH3:1][O:2][C:3]1[C:8]2[N:9]=[CH:10][S:11][C:7]=2[CH:6]=[CH:5][CH:4]=1.C(O[C:17](=O)[NH:18][C@H:19]1[CH2:24][CH2:23][C@H:22]([C:25](=[O:30])N(OC)C)[CH2:21][CH2:20]1)(C)(C)C.[O:32]=[C:33]1[NH:38][C:37]2[CH:39]=[C:40](C=O)[CH:41]=[CH:42][C:36]=2[O:35][CH2:34]1>>[CH3:1][O:2][C:3]1[C:8]2[N:9]=[C:10]([C:25]([C@H:22]3[CH2:21][CH2:20][C@H:19]([NH:18][CH2:17][C:40]4[CH:41]=[CH:42][C:36]5[O:35][CH2:34][C:33](=[O:32])[NH:38][C:37]=5[CH:39]=4)[CH2:24][CH2:23]3)=[O:30])[S:11][C:7]=2[CH:6]=[CH:5][CH:4]=1

참가 물질

4

반응물 3

HCID 107736383-oxo-3,4-dihydro-2H-1,4-benzoxazine-6-carbaldehydeHCID 126318584-Methoxy-1,3-benzothiazoleHCID 178502731HCID 178502731, 화합물

생성물 1

HCID 178489236HCID 178489236, 화합물

실험 절차

The title compound was prepared according to the same protocol as that described for example 1, steps 1.a to 1.c, using 4-methoxy-benzothiazole (5 mmol), [trans-4-(methoxy-methyl-carbamoyl)-cyclohexyl]-carbamic acid tert-butyl ester (2.5 mmol) and 3-oxo-3,4-dihydro-2H-benzo[1,4]oxazine-6-carbaldehyde (0.3 mmol). An orange solid (74 mg) was obtained.

출처 및 근거

ORD 기록
ord-a7ce56630155459286ed9c6b10670c7e
출처 데이터셋
uspto-grants-2011_07
특허 번호
US07981886B2

연결된 노트

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