Trifluoroacetic acid → 3-[[4-(Benzenesulfonyl)-5-oxido-1,2,5-oxadiazol-5-ium-3-yl]oxy]propanoic acid

반응식

[O-:1][N+:2]1[O:6][N:5]=[C:4]([O:7][CH2:8][CH2:9][C:10]([O:12]C(C)(C)C)=[O:11])[C:3]=1[S:17]([C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1)(=[O:19])=[O:18].C(O)(C(F)(F)F)=O>ClCCl>[O-:1][N+:2]1[O:6][N:5]=[C:4]([O:7][CH2:8][CH2:9][C:10]([OH:12])=[O:11])[C:3]=1[S:17]([C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1)(=[O:18])=[O:19]

참가 물질

실험 절차

14 g of the compound obtained in Step A dissolved in 100 ml of dichloromethane are placed under argon, 10 ml of TFA are added, and then stirring is carried out for 6 hours at ambient temperature.

출처 및 근거

ORD 기록: ord-a1e53ebe28ac4c42873f3439d7ccbf24
출처 데이터셋: uspto-grants-2011_07
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07981920B2

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참가 물질

반응물 2

HCID 6422Trifluoroacetic acid

HCID 86629015tert-Butyl 3-[(5-oxido-4-(phenylsulphonyl)-1,2,5-oxadiazol-3-yl)-oxy]-propionate

생성물 1

HCID 576261723-[[4-(Benzenesulfonyl)-5-oxido-1,2,5-oxadiazol-5-ium-3-yl]oxy]propanoic acid

시약·촉매·용매 1

HCID 6344Dichloromethane용매

실험 절차

14 g of the compound obtained in Step A dissolved in 100 ml of dichloromethane are placed under argon, 10 ml of TFA are added, and then stirring is carried out for 6 hours at ambient temperature.

출처 및 근거

ORD 기록: ord-a1e53ebe28ac4c42873f3439d7ccbf24
출처 데이터셋: uspto-grants-2011_07
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07981920B2

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불러오는 중…