Hexane → HCID 178516446, 화합물

HRID 1013706노트

반응식

HRID 1013706 반응식
CC1(C)O[C:6](=[O:8])[C:5](=[CH:9][NH:10][C:11]2[CH:16]=[CH:15][N:14]=[CH:13][CH:12]=2)C(=O)O1.CCCCCC>C1(OC2C=CC=CC=2)C=CC=CC=1>[N:10]1[C:11]2[C:12](=[CH:13][N:14]=[CH:15][CH:16]=2)[C:6]([OH:8])=[CH:5][CH:9]=1

참가 물질

4

반응물 2

HCID 8058HexaneHCID 59427333HCID 59427333, 화합물

생성물 1

HCID 178516446HCID 178516446, 화합물

시약·촉매·용매 1

HCID 7583Diphenyl Ether용매

실험 절차

A solution of 2,2-dimethyl-5-((pyridin-4-ylamino)methylene)-1,3-dioxane-4,6-dione (1.149 g, 4.63 mmol) in diphenyl ether was heated at 200° C. for 20 min, then cooled to RT. Hexane was added and the mixture was stirred at RT for 30 mins. The solid was filtered off and washed with hexane to furnish 1,6-naphthyridin-4-ol as an off-brown solid.

후처리

  1. filtrationThe solid was filtered off
  2. washwashed with hexane

출처 및 근거

ORD 기록
ord-267ed64a8b2f41e38cae9e1febb81757
출처 데이터셋
uspto-grants-2011_07
특허 번호
US07981891B2

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