(Diethylamino)sulfur trifluoride → Tert-butyl 3-(3-(cyclohexylmethoxy)phenyl)-2-fluoropropylcarbamate

반응식

[CH:1]1([CH2:7][O:8][C:9]2[CH:10]=[C:11]([CH2:15][CH:16](O)[CH2:17][NH:18][C:19](=[O:25])[O:20][C:21]([CH3:24])([CH3:23])[CH3:22])[CH:12]=[CH:13][CH:14]=2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.CCN(S(F)(F)[F:33])CC>>[CH:1]1([CH2:7][O:8][C:9]2[CH:10]=[C:11]([CH2:15][CH:16]([F:33])[CH2:17][NH:18][C:19](=[O:25])[O:20][C:21]([CH3:24])([CH3:23])[CH3:22])[CH:12]=[CH:13][CH:14]=2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1

참가 물질

반응물 2

HCID 123472(Diethylamino)sulfur trifluoride

HCID 58027630HCID 58027630, 화합물

생성물 1

HCID 67317096Tert-butyl 3-(3-(cyclohexylmethoxy)phenyl)-2-fluoropropylcarbamate

실험 절차

tert-Butyl 3-(3-(cyclohexylmethoxy)phenyl)-2-hydroxypropylcarbamate and DAST are reacted together to give tert-butyl 3-(3-(cyclohexylmethoxy)phenyl)-2-fluoropropylcarbamate.

출처 및 근거

ORD 기록: ord-7bd5f995d68440839da95ca7a019ef03
출처 데이터셋: uspto-grants-2011_07
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07982071B2

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