Phosphorus oxide (P4O10) → 7-Chloro-3,4-dihydro-1-methylisoquinoline

HRID 1015030노트

반응식

HRID 1015030 반응식
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][CH2:9][NH:10][C:11](=O)[CH3:12])=[CH:4][CH:3]=1.O=P12OP3(OP(OP(O3)(O1)=O)(=O)O2)=O>>[Cl:1][C:2]1[CH:7]=[C:6]2[C:5]([CH2:8][CH2:9][N:10]=[C:11]2[CH3:12])=[CH:4][CH:3]=1

참가 물질

3

반응물 2

HCID 14812Phosphorus oxide (P4O10)HCID 9877644N-[2-(4-chlorophenyl)ethyl]acetamide

생성물 1

HCID 110952137-Chloro-3,4-dihydro-1-methylisoquinoline

실험 절차

In close analogy to the procedure described above, N-[2-(4-chloro-phenyl)-ethyl]-acetamide is reacted with phosphorus pentoxide to provide the title compound.

출처 및 근거

ORD 기록
ord-9f453720fe8644fe88ad7d48eccc2325
출처 데이터셋
uspto-grants-2011_07
특허 번호
US07985753B2

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