Phosphorus oxide (P4O10) → 5-Bromo-1-methyl-3,4-dihydro-isoquinoline

HRID 1015037노트

반응식

HRID 1015037 반응식
[Br:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:8][CH2:9][NH:10][C:11](=O)[CH3:12].O=P12OP3(OP(OP(O3)(O1)=O)(=O)O2)=O>>[Br:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]2[C:3]=1[CH2:8][CH2:9][N:10]=[C:11]2[CH3:12]

참가 물질

3

반응물 2

HCID 14812Phosphorus oxide (P4O10)HCID 10868448N-(2-bromophenethyl)acetamide

생성물 1

HCID 584164875-Bromo-1-methyl-3,4-dihydro-isoquinoline

실험 절차

In close analogy to the procedure described above, N-[2-(2-bromo-phenyl)-ethyl]-acetamide is reacted with phosphorus pentoxide to provide the title compound.

출처 및 근거

ORD 기록
ord-701b896ae72b4459b898db25aff94938
출처 데이터셋
uspto-grants-2011_07
특허 번호
US07985753B2

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