Boronic Acid → 6-(3-Pyridyl)-1,2,3,4-tetrahydroisoquinoline

반응식

Br[C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[CH2:8][NH:7][CH2:6][CH2:5]2.B(O)O>>[N:7]1[CH:8]=[CH:9][CH:4]=[C:5]([C:2]2[CH:3]=[C:4]3[C:9](=[CH:10][CH:11]=2)[CH2:8][NH:7][CH2:6][CH2:5]3)[CH:6]=1

참가 물질

반응물 2

HCID 61668Boronic Acid

HCID 158851836-Bromo-1,2,3,4-tetrahydroisoquinoline

생성물 1

HCID 584163586-(3-Pyridyl)-1,2,3,4-tetrahydroisoquinoline

실험 절차

In close analogy to the procedure described above, 6-Bromo-1,2,3,4-tetrahydro-isoquinoline is reacted with the corresponding boronic acid to provide the title compound.

출처 및 근거

ORD 기록: ord-eb801d94d433453ba7c2d4b1cbbabd2b
출처 데이터셋: uspto-grants-2011_07
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07985753B2

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